Risk-benefit associated with Azithromycin: A brief review
Journal Title: Journal of Pharmacovigilance and Drug Research - Year 2020, Vol 1, Issue 20201201
Abstract
Azithromycin is the most popular prescribed antimicrobial agent around the world. It comes under the class of macrolide antibiotics. Because of its higher efficacy, tolerance, and broad-spectrum activity, it is primarily used in upper and lower respiratory tract infections, some sexually transmitted infections, and major bacterial infections. Generally, this is commercially available in solids, liquids, and ophthalmic formulations due to its minimal adverse events. It is also using in the case of COVID-19 drug therapy due to its pharmacological and therapeutic properties but a review of literature presented that it may increase the risk of cardiac death, hepatic injury, ototoxicity, hypersensitivity reactions.
Authors and Affiliations
Anil Kumar Pradhan1*, Ajit Nahak2, Gyanendra Narayan Mohapatra1
Artificial Neural Network: A Data Mining Tool in Pharmacovigilance
Pharmacovigilance ensures patients safety as well as drug safety. In India, there is still a lot to be done and learned to ensure that the work and activities done in the area of pharmacovigilance are safely implemented....
Overview of important methods used for Causality Assessment of adverse drug events in Pharmacovigilance
The method of assessing causality between adverse events and suspect drugs is the most challenging task in pharmacovigilance. It requires attentive consideration of both the adverse events and suspect drugs, patient-rela...
Design, synthesis, characterization and in vivo studies of some hydroxylated chalcone derivatives as hypoglycemic agents
Low molecular weight ligands (LMWL) have citadel reputation in the modulation of numerous therapeutic targets as a result of their smart uniqueness. The hydroxylated chalcone derivatives have been reported to be therapeu...
A Review on Potential Drug Delivery System as a Treatment of Intercellular Bacterial Infection
Intracellular bacterial pathogens are hard to treat because of the inability of conventional antimicrobial agents belonging to widely used classes, like aminoglycosides and β-lactams, fluoroquinolones, or macrolides to p...
Toxic epidermal necrolysis associated with combination therapy of spironolactone and torsemide
Dytor plus tablet is a fixed-dose combination of torsemide and spironolactone used for generalized edema. TEN is a serious, potentially life-threatening dermatological disorder. Here we present a case report of a 47-year...