Risk Factors And Seasonal-Diurinal Variatons In Lacunar Infarctions
Journal Title: Journal of Neurological Sciences-Turkish - Year 2006, Vol 23, Issue 2
Abstract
Lacunar infarctions are deeply located ischemic infarctions smaller than 1.5 cm in diameter. Patients hospitalized in our neurology clinic in between 2001 and 2005 with signs of lacunar infarction and in whom diagnosis were confirmed with neuroimaging studies, were included in this study. Risk factors and time of symptom-onset were re-evaluated by use of phone calls with them and/or their relatives. Eighty-one patients with mean age of 64.6 were involved in the study. Forty-three of them (%53) were female. The lesion was in left hemisphere in forty-five patients (%55.6), and in right hemisphere in remaining 36 (%44.4) ones. There was at least one vascular risk factor in 80 of them (%98.8), and a cardiac one in 6 patients (%7.4). Sixty-five patients (%80.2) had multiple vascular risk factors. There was hypertension in 68 (%83.9), dyslipidemia in 48 (%59.2), smoking in 26 (%32.1), and diabetes mellitus in 22 (%27.2) of them. Among 16 patients with single risk factor, 10 patients had hypertension and 6 patients had dyslipidemia. In 34 of them (%41.9), symptoms had appeared during night-time (sleeping + first hour of awakeness), and in 47 of them (%58.1) during day-time. The disease was seen during winter in 17 (21%), spring in 22 (27.2%), summer in 19 (23.4%), and autumn in 23 (28.3%) of them. After analyses were corrected according to risk factors, sex and age, any seasonal-diurnal variation or side differences were not detected. Presence of many patients with single risk factor reveals the importance of primary prophylaxis clearly. High frequency of multiple risk factors underlines needs for use of preventive treatment carefully in these patients.
Authors and Affiliations
Murat ALEMDAR, Pervin ISERİ, Senol KAMACI, Husnu EFENDI, Faik BUDAK, Sezer KOMSUOGLU
Keywords
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