Role of Adenosine Deaminase in Tubercular Pleural Effusion as a Diagnostic Index
Journal Title: International Journal Of Research In Medicine - Year 2014, Vol 3, Issue 2
Abstract
BACKGROUND: Tubercular pleural effusion is a common manifestation of extra-pulmonary tuberculosis. Adenosine Deaminase (ADA) is a biological marker that is useful in the diagnosis of tubercular pleural effusion. The aim of this prospective observational study was to study the level of ADA in pleural fluid and evaluate its usefulness in the diagnosis of tubercular pleural effusion. MATERIALS AND METHODS: The study was conducted on 50 patients with pleural effusion attending a tertiary care Teaching Institute. RESULTS: Considering a cut-off value of pleural fluid ADA as 40 IU/L, ADA was found to be positive in 32 out of 34 cases with tubercular pleural effusion. CONCLUSION: Pleural fluid ADA estimation has a valuable role in the diagnosis of tubercular pleural effusion.
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