Role of Carotid Intima Media Thickness As A Surrogate Marker of Cardiovascular Events
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 2
Abstract
Introduction: Cardiovascular events are acquiring important dimensions. Atherosclerosis is the main cause of reduction in regional blood flow. Screening modalities to evaluate subclinical atherosclerosis are significant for preventing cardiovascular events. Study aimed to evaluate role of carotid intima - media thickness (CIMT) as a surrogate marker of cardiovascular events. Objectives: To measure common carotid artery intima - media thickness (IMT) and internal carotid artery intima - media thickness (CIMT). Material and Methods: Carotid B - mode ultrasonography (USG) was done prospectively in 200 individuals. Of them 100 cases were patients with complaint of chest pain with positive electrocardiogram (ECG) findings or elevated cardiac enzymes or both. 100 cases were patients with no present or past history of chest pain with positive electrocardiogram (ECG) findingsor elevated cardiac enzymes or both. Results: In this study, Carotid intima - media thickness (CIMT) was measured in both cases and control groups bilaterally. The mean levels of common carotid artery (CCA) were 0.12 mm in cases and 0.05 mm in control and the mean levels of internal carotid artery (ICA) were 0.12 mm in cases and 0.06 mm in controls. Conclusion: The study significantly shows the correlation between increased CIMT and cardiovascular events. CIMT can act as surrogate marker in CVS events as it assesses degree of subclinical atherosclerosis. It is highly effective due to its non invasive nature, low economic cost and easy availability.
Authors and Affiliations
Sudhir Sachar, Vimugdha Premi, Ila Pahwa, Saurabh Sachar, Sukriti Verma, Ubaid UR Rehman
Keywords
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