Serum Calcium and Electrolytes in Hypothyroidism - A Case Control Study
Journal Title: International Journal of Contemporary Medical Research - Year 2016, Vol 3, Issue 3
Abstract
Introduction: Hypothyroidism is the most common form of endocrine abnormality resulting from the deficiency of thyroid hormones or from their impaired activity. Different electrolyte disorders in association with thyroid dysfunction were observed in the literature. The effect of thyroid hormones on minerals has not been well established and the underlying mechanism is not well understood too. So, the present study was undertaken to assess the alterations in the levels of serum calcium, sodium, potassium and chlorides and to correlate these minerals with TSH in hypothyroidism. Materials and methods: A case control study is taken up on 40 subjects with hypothyroidism and 40 apparently normal healthy subjects. Venous blood sample is collected from all the subjects. Serum TSH, calcium, sodium, potassium and chlorides are estimated in all the subjects. Results: A significant decrease in serum calcium, sodium and potassium is observed in cases in comparison to controls (p<0.0001). A significant increase in serum chlorides is observed in cases (p=0.03) compared to controls. When correlated with TSH, serum calcium, sodium, potassium and chlorides showed negative correlation in subjects with hypothyroidism. Conclusion: The present study indicates the profound influence of thyroid hormones on serum electrolytes. This study concludes that serum calcium, sodium and potassium levels are decreased whereas serum chloride levels are increased in hypothyroidism in comparison to euthyroid subjects. We suggest that hypothyroid patients should be regularly monitored for serum electrolytes. Monitoring of these parameters in hypothyroidism will be of great help in its management.
Authors and Affiliations
Amrut A Dambal, D. Sridevi, Sidrah . , Samata K Padaki
Keywords
Related Articles
- EP ID EP426925
- DOI -
- Views 92
- Downloads 0
Speciation, Characterization and Antifungal Susceptibility Pattern of Candida Species
Introduction: The incidence of Candida has been on the rise worldwide. Urinary tract infections as a result of Candida species are becoming common in hospitalized patients. The species identification of Candida is import...
Gender Based Profiling of Opportunistic Infections in AIDS Patients in Tertiary Care ART Centre of A Cosmopolitan City of Central India
Introduction: In HIV/AIDS, Women appeared to have more rapid progression of illness than men and to present with a different constellation of opportunistic infections than men. Objective of the study was to compare the g...
A Comparative Interventional Study Using Single Port and Double Port Methods in Diagnostic Laparoscopy for Evaluation of Cases of Infertility
Introduction: Overall incidence of infertility is 10-15%.Of all the couples attempting to conceive, 16% are unsuccessful after one year, this reduce to 8% after 2 years and 7% after 3 years. The aim of this study to comp...
Correlation of Serum Pseudocholinesterase Level and Peradeniya Organophosphorus Poisoning Scale with the Severity and Inhospital Outcome of Acute Organophosphorus Poisoning
Introduction: Organophosphorus (OP) compounds are commonly used for suicide in rural India. The rate of OP poisoning as a suicidal agents ranges from 10.3% to 43.8% in various studies in India. So present study was done...
Current Leprosy Scenario at a Tertiary Care Hospital in Uttarakhand
Introduction: Despite elimination, Leprosy continues to be a major public health problem in India. According to World Health Organisation’s (WHO) data for year 2014, Indian contribution for global leprosy is more than 60...