Role of CRP, Micro- ESR and CPIS in Diagnosis of Ventilator Associated Pneumonia in Neonates at a Tertiary Care Hospital in Rajasthan.
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2019, Vol 4, Issue 4
Abstract
Background: With increase in use of ventilator in NICU, Ventilator Associated Pneumonia has become a significant factor affecting the neonatal survival. Prevention with appropriate management of VAP requires early diagnosis. Methods: Hospital based observational study conducted on all children below 1 month of age kept on mechanical ventilation for at least 48 hrs & admitted in Intramural NICU (patient directly admitted in NICU) and Extramural NICU (patients referred from other hospital) . Results: Of 132 neonates who needed mechanical ventilation, 50(37.9%) developed VAP. Out of 50 cases who developed VAP, CRP was positive in 37 cases(52.1%) and 39 patients(81.2%) had CPIS >6. Sensitivity for CRP and CPIS was found to be 74% and 78% and specificity was 58.5% and 86.9% respectively while the positive predictive values were 52.1% and 81% and negative predictive values were 78.6% and 82% respectively. Significant risk factors associated with VAP were prematurity(OR=2.23), ventilation at early neonatal age(OR=2.5) and prolonged ventilation(OR=2.98). Conclusion: VAP contributes significantly to hospital acquired infection among neonates. Both CPIS and CRP were useful in screening the cases of VAP in neonates. When used in conjuction the tests were able to predict VAP even better.
Authors and Affiliations
G. S. Sengar
Keywords
Related Articles
- EP ID EP552716
- DOI -
- Views 113
- Downloads 0
Prevalence of Anxiety and Depression in Chronic Obstructive Pulmonary Disease (COPD).
AIM: To know the prevalence and severity of anxiety and depression in chronic obstructive pulmonary disease (COPD) patients. Materials and Methods: A Hospital Based cross sectional study was conducted in COPD PATIENT...
Evaluation of Vitamin D levels in Metabolic syndrome and its correlation with glycemic profile and cardiovascular risk factors
Aims: Evaluation of Vitamin D levels in people with metabolic syndrome and to evaluate the relationship between Vitamin D and traditional Cardiovascular disease risk factors [blood pressure, FBS/PPBS, obesity, dyslipidem...
Cerebellar ataxia associated with Hashimotos Thyroiditis totally responsive to steroid therapy.
44 years old female known case of hypothyroidism in euthyroid state presented with features suggestive of cerebellar ataxia. As her serum Anti-TPO antibodies were high, she was suspected to have Hashimotos thyroiditis, f...
Effect of Mode of Transport on Outcome of Sick Children Requiring Emergency Care – A Cohort Study
Objective To determine whether mode of transport has any effect on outcome of children requiring emergency care. Methods This observational study was conducted in ICH&HC from April 2014 to June 2014. All consecutive chil...
Frequency of Kell Blood Group Antigen in Voluntary Blood Donors
Background: The data on incidence of antigens of various blood groups in the local donor population helps in routine blood transfusion practices of a blood transfusion centre. It is important to know the frequencies of t...