Role of D-Dimer Assay in Early Detection of Suspected Deep Vein Thrombosis in Obese Individuals

Journal Title: New Indian Journal of Surgery - Year 2018, Vol 9, Issue 1

Abstract

Background: Role of D-dimer assay in suspected high risk obese patients has not been explored much. Therefore, purpose of this study is to ascertain the place of D-dimer assay in diagnosis of Deep vein thrombosis (DVT) in obese patients. Methods: Patients attending outdoor or admitted in surgery ward of hospital, presenting with history and examination suggestive of DVT, at high risk of developing DVT and having Body Mass Index >25 kg/m2 were included. D-dimer assay and ultrasonography (USG) was done at the time of admission, ultrasound was repeated at one week (if the first examination was negative for DVT) and at one month. Out of total 70 suspected cases, D-dimer levels were compared in relation to cases which were finally diagnosed as DVT by USG and those in whom DVT was excluded. Sensitivity, specificity, positive predictive value, and negative predictive value for the D-dimer test were calculated. Results: 70 suspected cases of DVT (32 males & 38 females) were included with mean age of 55.59±13.59 y and with mean BMI of 27.7±1.7. No statistical difference between vital parameters of diagnosed and excluded cases of DVT was found. The sensitivity and specificity of D dimer were found to be 100.0% & 35.5% respectively. Positive predictive value was 46.29% and Negative predictive value was 100.0%. Conclusions The sensitivity and negative predictive value of semiquantative latex D-dimer assay for deep venous thrombosis are high. Deep vein thrombosis in obese individuals can be ruled out on the basis of D-dimer assay.

Authors and Affiliations

Dixit Pawan K.

Keywords

Related Articles

Mannheim Peritonitis Index Scoring System as Predictor of Prognosis in Acute Peritonitis

Background and Objectives: With the advances that are being made in many areas of medicine, the surgeon must be familiar with infectious diseases of the peritoneal cavity which has increased in severity and complexity. O...

A Prospective Study on Role of Serum TSH in Predicting Thyroid Malignancies

Background: Thyroid cancer is the most common endocrine malignancy and its incidence continues to rise. Thyroid carcinoma in most cases presents clinically as a solitary nodule or as a dominant nodule within a multinodul...

Evaluation of Prognosis in Patients’ with Perforation Peritonitis Using Mannheim’s Peritonitis Index

Background: Perforation peritonitis is quite common surgical emergency in India as well as worldwide. There are various prognostic indexes available for evaluation of prognosis in patients with peritonitis but none of th...

A Clinical Study of Effectiveness of Sac Eversion with Minimal Separation in the Treatment of Hydrocele

Context: Primary vaginal hydrocele is commonest disease worldwide. In tropics lymphatic filariasis is main cause. Surgery is treatment of choice. A number of methods are described. “Sac eversion with minimal separation”...

A Comparative Study between Figure of Eight Suturing Technique and Omentopexy in Closure of Peptic Ulcer Perforationin a Rural Medical College of Karnataka

Background: Figure of 8 techniques has been described in the literature for peptic ulcer perforation repair especially when the patient comes late, when the edges of the ulcer and the wall of duodenum are very friable. M...

Download PDF file
  • EP ID EP542318
  • DOI 10.21088/nijs.0976.4747.9118.6
  • Views 97
  • Downloads 0

How To Cite

Dixit Pawan K. (2018). Role of D-Dimer Assay in Early Detection of Suspected Deep Vein Thrombosis in Obese Individuals. New Indian Journal of Surgery, 9(1), 32-36. https://europub.co.uk/articles/-A-542318