Role of Dexmedetomidine as an Anesthetic Adjuvant in Laparoscopic Surgery
Journal Title: People's Journal of Scientific Research. - Year 2015, Vol 8, Issue 2
Abstract
Dexmedetomidine is a highly selective agonist with properties of sedation, analgesia and anxiolysis, making it an ideal anesthetic adjuvant. Using an anesthetic adjuvant decreases the requirement of anesthetics and analgesics. We studied 60 patients of ASA grade I and II, aged between 18 to 50 years, of either gender posted for laparoscopic surgeries under general anesthesia. Patients were randomly allocated in one of the two parallel groups containing 30 patients each. Group D received Dexmedetomidine infusion at the rate of 1 mcg/kg for 20 minutes and then maintenance infusion of 0.2 mcg/kg/min till extubation. Control group NS received normal saline. Induction with propofol and fentanyl was carried out. Patients were monitored with standard monitoring. A reduction in the induction dose of propofol was observed, with a 30% less end-tidal concentration of isoflurane requirement for maintenance of anesthesia. Dexmedetomidine a highly selective alpha 2 agonist is an effective anesthetic adjuvant that can be safely used in laparoscopy.
Authors and Affiliations
Vaisahali Waindeskar, Munir Khan, Shankar Agarwal, M Gaikawad
Keywords
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