Role of free radicals and antioxidants in cervical cancer in southern part of Rajasthan
Journal Title: International Journal of Clinical Biochemistry and Research - Year 2018, Vol 5, Issue 4
Abstract
Introduction Present study is conducted to measure the role of free radicals malondialdehyde and vitaminC and vitaminE in cervical cancer women in southern part of RajasthanMaterials and Methods Total 80 cases and controls were taken and level of MDA were determined by the Thiobarbituric acid TBA test which is the colorimetric reaction of MDA and TBA in acid solution Vitamin C was determined by the method of Natelson 1971 Vitamin E was determined by Baker and Frank methodResults The serum level of malondialdehyde vitaminC and vitaminE level in cervix cancer patients and controls using paired ttest for independent means and found that a statistically significant difference exist between case and controlsConclusion Present study concluded that serum levels of vitamin C and vitamin E decreases and level of MDA increases in cervix cancer patients So the serum levels of these micronutrients as a marker in early diagnosis of cervix cancer as adjuvant to other methods as well as by providing supplementation of these micronutrientsKeywords Cervix carcinoma Malondialdehyde Oxidative stress Polyunsaturated fatty acid Thiobarbituric acid reactive substances Antioxidant vitamins
Authors and Affiliations
Priyanka Dr, Dharmveer "Dr", Vinay "Dr"
Keywords
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- EP ID EP475430
- DOI 10.18231/2394-6377.2018.0118
- Views 84
- Downloads 0
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