Role of histopathology in diagnosis of leprosy- A tertiary care hospital based study

Journal Title: IP Journal of Diagnostic Pathology and Oncology - Year 2018, Vol 3, Issue 4

Abstract

Introduction Leprosy is continuous spectrum of varied clinicopathological manifestations of the disease1 leprosy still continues to be one of major health problem due to consequent disabilities and social stigma23 Timely diagnosis helps in proper treatment and reduce the chances of recurrence It is chronic infection which affects skin and peripheral nerves45 The nerve biopsies are difficult diagnosis mainly depends upon clinical examination of skin lesions and histopathological diagnosis Most of leprosy cases were diagnosed without histopathological examination6 The aim of the present study was to know the Role of skin biopsy in diagnosing leprosy casesMaterials and Methods This was a cross sectional comparative study of skin biopsies of clinically suspected or diagnosed leprosy cases coming to the tertiary care hospitalResults Sixty two 62 biopsies were included in the study All biopsies were classified histologically compared with clinical diagnosis Out of 62 cases BB was the main clinical diagnosis comprising 19306 followed by BL 16258 LL 11178 IND 9145 BT 581 and TT 232 remaining Out of these 62 cases 40 645 cases histopathological diagnosis were agreed with clinical diagnosisConclusion Histological examination is an important tool in the accurate diagnosis of leprosy Indeterminate and borderline leprosy cases diagnosed on clinical grounds are difficult due to it39s varied presentation and could mimic with other diseases therefore histopathological examination is useful to confirm diagnosis and accurate typing of leprosy for proper treatmentKeywords Leprosy histopathology TTtuberculoid BTBorderline Tuberculoid BBBorderline Borderline BLBorderline Lepromatous LLLepromatous leprosy

Authors and Affiliations

R S A Kiran Singh, Mahathi Thotakura, Aruna Chintaginjala

Keywords

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  • EP ID EP482799
  • DOI 10.18231/2581-3706.2018.0065
  • Views 109
  • Downloads 0

How To Cite

R S A Kiran Singh, Mahathi Thotakura, Aruna Chintaginjala (2018). Role of histopathology in diagnosis of leprosy- A tertiary care hospital based study. IP Journal of Diagnostic Pathology and Oncology, 3(4), 326-329. https://europub.co.uk/articles/-A-482799