Role of imprint cytology and frozen section in the diagnosis of tumours
Journal Title: Pathology Update: Tropical Journal of Pathology and Microbiology - Year 2018, Vol 4, Issue 8
Abstract
Introduction: Imprint cytology is an economical, simple and quick method with excellent cytological clarity but cannot provide information on the depth of invasion. Frozen section is the standard method of intraoperative diagnosis but is limited by its cost, need of qualified technical staff and the freezing arte facts. Thus, both the techniques have their own limitations and combining these techniques helps in achieving high diagnostic accuracy rates. Aims: 1. To assess the combined role of imprint cytology and frozen section in the diagnosis of tumours of various organs. 2. To compare the diagnostic accuracy of imprint cytology and frozen section individually with that of the histopathological diagnosis. Materials and Methods: The present study was done in the pathology department of Bangalore medical college and research institute for a period of one year. A total of 50 surgical specimens from various organs were studied using imprint cytology and frozen section. The results of both the techniques were compared with the gold standard histopathological diagnosis. Results: Out of 50 cases, majority were ovarian neoplasms comprising of 21 (42%) cases followed by thyroid (14%), breast (12%) and salivary gland (10%) neoplasms. The majority of the cases were malignant (50%) followed by beingn (40%), borderline (6%) and metastatic (4%). The overall diagnostic accuracy of imprint cytology and frozen section in various organs were 94% and 98%respectively. The combined diagnostic accuracy was 98%. Conclusion: Imprint cytology and frozen sections are interdependable intraoperative diagnostic modalities. Imprint cytology alone may not be able to provide a correct diagnosis. Thus, a combination of imprint cytology and frozen section helps in achieving high diagnostic accuracy rates and in distinguishing benign and malignant lesions.
Authors and Affiliations
Shubha. H. V. , Arun. H. N, Nirmala. C. , Dayananda. S. Biligi
Keywords
Related Articles
- EP ID EP499984
- DOI 10.17511/ jopm. 2018.i8.06.
- Views 138
- Downloads 0
Congenital malformations of gastrointestinal tract in children aged less than 5 years of age: A retrospective and prospective study
Introduction: The spectrum and prevalence of congenital abnormalities of gastrointestinal tract vary in different populations depending upon the environment influences, genetic predisposition and prevalent socioeconomic...
A study of neoplastic study of gastrointestinal tumors
Background: Gastrointestinal tumors account for a large proportion of all neoplasms. The tumors of the Gastrointestinal tract pose a major problem in oncology and also are a major cause of apprehension in patient with th...
Pilomatricoma masquerading as a parotid mass in a child-a diagnostic challenge on cytology
Pilomatrixoma is a slow growing benign skin neoplasm of hair matrix origin. This tumor is common in children and young adults, especially in the head and neck region. Because of its varied morphological spectrum on cytol...
Incidence of infections with extended spectrum beta Lactamase (ESBL)-producing gram-negative bacteria among patients admitted in medical intensive care unit of tertiary care hospital
Introduction: Extended spectrum beta-lactamases (ESBLs) are beta-lactamases capable of conferring bacterial resistance to the Penicillins, first, second and third generation cephalosporins, and Aztreonam (but not the Cep...
Retrospective analysis of head and neck masses diagnosed by cytology in a tertiary care centre
Introduction: Fine Needle Biopsy of head and neck masses as a minimally invasive technique is particularly suitable in this sensitive area where an incisional biopsy can cause problems. A cytological diagnosis of a non-n...