Role of Prophylactic Antibiotics in Low Risk Elective Laparoscopic Cholecystectomy: A Randomized Controlled Study
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 6
Abstract
Introduction: Elective laparoscopic cholecystectomy for symptomatic cholelithiasis has low risk of postoperative infective complications. Although antibiotics prophylaxis is routinely administered in laparoscopic cholecystectomy, its role is debatable. Our objective of this study was to explore the adequacy of anti-microbial prophylaxis in avoiding postoperative infective intricacies in low risk elective laparoscopic cholecystectomy patients. Material and Methods: From June 2014 to Dec 2016, 300 patients were randomized into 138 in antibiotic group (ABG) and 162 in non antibiotics group(NABG). AG received single dose of injection Ceftriaxone 1 grm and ornidazole 500mg as prophylactic antibiotics(according to our institutional practice protocol) at the time of induction of anesthesia. NAG was given only intravenous fluids. Besides routine care in both groups age, gender, surgical duration, ASA classification, and duration of stay in hospital were documented. Patients were followed-up week by week for 4 weeks and rates of shallow surgical site contaminations and in addition intra-abdominal infections were assessed. Results: Both groups were analogous in patient’s clinicodemographic characteristics such as average Age (44.31 vs. 44.52 years) and sex (female 76.51% vs. 76.2%). Overall wound infection occurred in 4.33% (13/300). There was no significant difference observed in wound infections among the different groups (p =0.802): ABG 4.5% and NABG 4%. Conclusion: Antibiotics prophylaxis is not needed for low risk laparoscopic cholecystectomy
Authors and Affiliations
Aryal Rishi Kant, Gautam Rakchhya, Shrestha Nabin
Keywords
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