Role of Risk Malignancy Index in Predicting Ovarian Malignancy and its Correlation with Histopathological Report
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2015, Vol 3, Issue 1
Abstract
The aim of this study was to evaluate the accuracy of the Risk Malignancy Index in discriminating between benign lesions and malignant adnexal masses in gynaecologic practice by correlating with the postoperative histopathological report. The study was done in department of Obstetrics and Gynaecology at Cheluvamba Hospital, Mysore. During the period of May 2013 to August 2014 a total of 27 cases of adnexal masses were studied. On admission, detailed history and examination including preoperative laboratory work up was done. Pelvic USG scan and serum CA-125 done and Risk Malignancy Index (RMI-3) calculated for all patients. Post operatively histopathological reports collected and analyzed. Through the period of 1 yr 3 months, a total of 27 patients with adnexal mass were treated. Out of them 24 patients had benign and the remaining three had malignant adnexal masses. Each parameter constituting RMI was evaluated individually in order to determine its role in predicting malignancy. Of the 27 patients, 9 were menopausal. Whereas, the remaining 18 patients had regular menstrual cycle showing significantly more patients with malignant histopathology were in menopause. USG findings revealed a score of <2 in 19 cases and a score >2 in 8 cases. Further CA-125 of >35U/ml was seen in 5 cases, RMI was calculated using the formula (U*M*CA-125). High risk (RMI of >200) was seen in 4 cases, further narrowing the suspicion of malignancy more accurately in preoperative analysis of adenexal masses. RMI score using menstrual status, ultrasound score and serum CA-125 levels is a useful predictor in assessment of malignancy in ovarian tumors of epithelial origin.
Authors and Affiliations
R. C. Prameela, Gangavva Lokhapur, Priya Ranganath
Keywords
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