Role of Serum Bilirubin in Coronary Artery Disease
Journal Title: International Journal of Medical and Health Sciences - Year 2012, Vol 1, Issue 2
Abstract
Lipid oxidation and formation of oxygen radicals are important elements of arterial plaque formation and atherosclerosis, and are involved in the pathophysiology of coronary artery disease (CAD). Since bilirubin has antioxidant properties, it has been suggested that it may have a protective role in the atherosclerotic process by preventing formation of oxidized LDL. The antioxidant capacity of bilirubin and its ability to provide potent scavenging effect of peroxyl radicals have led to suggest that mild increase in the circulatory bilirubin may have a physiologic role to protect against the disease processes that involve oxygen and peroxyl radicals.This review briefly examines the role of bilirubin and its protective function against the coronary artery disease. KEYWORDS: Bilirubin, Antioxidant activity, Cardiovascular disease.
Authors and Affiliations
Veerendra Kumar Arumalla, Niranjan Gopal , Rao BN
Keywords
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