Role of Slit Skin Smear Examination and rK39 for Diagnosis of Post Kala-Azar Dermal Leishmaniasis
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 1
Abstract
Introduction: Post Kala-azar dermal leishmaniasis is a complication of visceral leishmaniasis characterised by multiple hypopigmented, macular, maculopapular or nodular rash on the face, trunk or other part of the body. It occurs mainly in the East Asia and the Indian Subcontinent behaving as major reservoir of parasite in areas of anthroponotic transmission. Materials and Methods: The study was aimed to analyse the role of Slit skin smear (SSS) examination and rK39 in the diagnosis of PKDL, in the Department of Microbiology, Patna Medical College, Patna. The study was conducted on 60 patients for the period of 1 year. Specimen was obtained from the site of lesion and material obtained was smeared uniformly on the microscopic slide. Fresh peripheral whole blood was drawn and serum was used for the rK39 test. Rapid test kit (InBios International Kala-azar detection kit) was used. Results: Out of 60 suspected cases of PKDL, on SSS examination 16 cases (26.67%) were positive for LD bodies while, on performing rK39 rapid kit test, 25 cases (41.67%) were found positive. Conclusion: Initial screening by serology (rK39 kit test) followed by confirmatory diagnosis of PKDL with SSS examination is simple and minimally invasive procedure for epidemiological studies and assessment of cure in PKDL.
Authors and Affiliations
Pratulya Nandan, Spriha Smriti, Babita Kumari, Anita Sundi, Swapnil Keshav
Keywords
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- EP ID EP529238
- DOI 10.21276/ijmrp.2018.4.1.022
- Views 109
- Downloads 0
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