Role of Tamsulosin in aiding spontaneous expulsion of lower ureteric calculi in patients on conservative therapy
Journal Title: MedPulse -International Medical Journal - Year 2015, Vol 2, Issue 7
Abstract
This is a prospective, single centered based observational study carried out at our rural medical college in Bihar in the period from 01 Jan 2014 to 30 Jun 2015.The present study was done to evaluate the role of Tamsulosin in aiding the spontaneous expulsion of distal ureteric calculi. Patients who were diagnosed to have distal ureteric calculi less than 10mm in size on initial imaging with X-Ray Kidney Ureter Bladder (KUB) or Ultrasonography (USG) KUB were included in the study. Proper Informed Consent was taken from every patient those who were included in this study. A sample size of 50 was taken for the study. The patients included in the study was divided into Group A and Group B corresponding to the Test and Control groups. Based on the calculus size, patients were further subdivided for the purpose of analysis of data. They were followed up on fortnightly basis or earlier, depending on the calculus expulsion with imaging (X-Ray KUB or USGKUB). The result thus obtained was analyzed statistically using the Chi Square test and unpaired t-Test at the end of the study. Two groups was made after randomly drawing out coupons from a closed box containing folded papers of equal size bearing the numbers 1 to 50. Patients were unaware of this group allocation. Group A composed of patients who was administered Cap Tamsulosin 0.4 mg HS along with Tab Diclofenac 50mg for pain relief while Group B composed of patients who received only Tab Diclofenac 50mg for symptomatic relief. Patients were asked to return for follow up fortnightly, or on spontaneous passage of calculus in the urine, whichever was earlier. The end point of the study was 1) Spontaneous stone passage by 4 weeks or earlier 2) Treatment discontinuation. At the end of the study, 24 patients (48%) passed calculus spontaneously in the total study group. Out of them, 17 patients (68%) were from Group A and 7 patients (28%) were from Group B.
Authors and Affiliations
Sanjeeva Kumar Choudhury, Ved Rajan Arya, Kaustav Saha
Keywords
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