ROLE OF TOPICAL APPLICATION OF SHRINGVERADI EYE DROPS IN NETRABHISYANDA WITH SPECIAL REFERENCE TO ALLERGIC CONJUNCTIVITIS
Journal Title: Journal of Biological and Scientific Opinion - Year 2015, Vol 3, Issue 4
Abstract
Ocular allergy manifests as a number of distinct disease entities, ranging from allergic conjunctivitis, a relatively mild condition, to keratoconjunctivitis, which may be sight-threatening condition affecting the cornea. Underlying immune mechanism behind this has not yet been fully understood, but it is known that IgE related mast cell and eosinophil mediated inflammation leads to the release of mast cell mediators and toxic eosinophil granule protein and enzymes. Patients suffering from ocular allergy might experience such symptoms such as redness, itching, burning, swelling or dryness in eyes in differing degrees of severity and duration. Based on clinical features Allergic conjunctivitis can be correlated with Abhisyanda of predominantly a Kaphaja etiology. The features like itching, edema of conjunctiva and lid, heaviness of eyelid indicate Kaphaja etiology of allergic conjunctivitis. Features like burning sensation indicate vitiation of Pitta. Dryness of eye indicates vitiation of Vata. Redness suggests vitiation of Rakta. Hence, features of allergic conjunctivitis are mainly linked with Kaphaja activity with subsidiary action of other doshas .To search a safe, potent and cost-effective Ayurvedic treatment for Netrabhisyanda a randomized control clinical trial was conducted on 67 patients. Patients were divided in three groups 25 in Group I (Control Group i.e. Ketotifen 0.025%), 27 in group II (trial Group i.e. Shringveradi Drops) and 15 in Group II I (Placebo i.e. Normal saline) treated topically four times per day for 14days.The effect of Ayurvedic management was found to be equivalent to the standard therapy and more effective than placebo, although the trial drug showed more effect in blepharitis and follicles in lower palpebral conjunctiva. Study shows that Shringveradi eye drops can be used as potent, safe and cost-effective treatment to ameliorate the symptoms of allergic conjunctivitis.
Authors and Affiliations
Sakshi Kanaujia , Manoj Kumar
Keywords
Related Articles
- EP ID EP133121
- DOI 10.7897/2321-6328.03437
- Views 104
- Downloads 0
CRITICAL APPRAISAL ON FORMULATIONS OF KOUSHEYASHMA (ASBESTOS)
Number of Metals and Minerals are described in Rasashastra (Iatrochemistry). Kousheyashma (Asbestos) is one such mineral drug listed under group of Sikata varga (Silicates). The details of this drug are not found in auth...
DETECTION OF SENSITIVE FOOD PATHOGENS IN BANANA, COLD MEAT AND MILK BY PCR AMPLIFICATION BASED TECHNIQUE
This study was carried out to detect Escherichia coli, Klebsilla spp. and Streptococcus spp. isolated from food samples (banana, cold meat and milk). The homogenized food samples were subjected to biochemical and molecul...
IMPACT OF DRYING CORIANDER HERB ON ANTIOXIDANT ACTIVITY AND MINERAL CONTENT
The present study investigated the impact of drying on quality, mineral content and antioxidant activity of coriander herb after four drying treatments. The coriander herb was subjected to different drying methods viz.,...
A REVIEW ON POLYMERS USED IN NOVEL IN SITU GEL FORMULATION FOR OCULAR DRUG DELIVERY AND THEIR EVALUATION
Ophthalmic drug delivery is one of the most interesting and challenging endeavours facing the pharmaceutical scientists, the major problem encountered to pharmaceutical scientist is rapid precorneal elimination of the dr...
ILAJ BIL GHIZA (DIETOTHERAPY): A CORE PRINCIPLE OF UNANI TREATMENT– AN APPRAISAL
Ghiza (diet) is one of the vital necessities of life. During prehistoric period most of the people considered diet only to satisfy their hunger pangs, but with the advent of medical science and preventive or community me...