Role of Topical Phenytoin in the Management of Diabetic Foot Ulcers
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2017, Vol 5, Issue 5
Abstract
Introduction: The management of the diabetic foot ulcer (DFU) is largely determined by its severity (grade), vascularity of the limb, and the presence of infection. In India, habits such as walking barefooted, lack of knowledge regarding diabetic foot, hot climate leading to increased perspiration, poor hygiene, poor sanitation, diet which has low proteins, and general poverty have worsened the problem. Aim: To study the effect of topical phenytoin in the management of DFU. Materials and Methods: A total of 40 patients with DFU were studied. 20 patients underwent surgical debridement, and conventional povidone-iodine dressing and 20 others received surgical debridement followed by topical phenytoin dressing. Results: DFU was common in patients with the duration of diabetes 5-10 years >70% belong to Wagner’s Grade 3 and 4 ulcers. On topical application of phenytoin, there was a significant decrease in pain but this was more subjective. There was a decrease in purulent discharge at the end of 1 week and significant negative culture at the end of 2 weeks. Conclusion: Considering phenytoin in accelerating wound healing it can be used as a safe, effective easy to use and inexpensive management in the treatment of DFU.
Authors and Affiliations
M S Varadarajan, M Gobinath, Heber Anandan
Keywords
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