Peripheral Nerve Dysfunction in Chronic Kidney Disease
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2018, Vol 5, Issue 10
Abstract
Introduction: Peripheral nerve dysfunction is a recognized complication of chronic kidney disease (CKD). The study mainly focuses the incidence, clinical manifestation, and severity of peripheral nerve dysfunction in patient with CKD admitted in our hospital. Aim: The aims of our study are to evaluate the incidence of overt neuropathy and subclinical neuropathy in CKD patients and to evaluate the clinical manifestations of peripheral nerve dysfunction. Methods: The study was conducted at the medical wards of Tirunelveli Medical College. Patients with proved clinical, biochemical parameters in favor of CKD, and all patients included in this study were not on dialysis. Results: Of 74 patients assessed, 48 patients proved to have peripheral nerve dysfunction by electrodiagnostic study and the number of patients affected with peripheral nerve dysfunction is increasing when the duration is increasing (more than 5 years). Conclusion: Distal symmetrical predominantly sensory motor neuropathy is the most common type of peripheral neuropathy observed in patients with CKD. Loss of ankle reflex and vibratory sensory loss are the most common clinical signs of peripheral neuropathy in patients with CKD. There is predilection for male in the incidence of peripheral neuropathy in CKD when the creatinine clearance was below 15 ml/mt.
Authors and Affiliations
G Rathnakumar, Jyothis P Jose, Heber Anandan
Keywords
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