ROLE OF VITAMIN D IN HYPOTHYRODISM
Journal Title: PARIPEX-Indian Journal of Research - Year 2019, Vol 8, Issue 5
Abstract
INTRODUCTION: Insufficiency of Vitamin D is a global health problem Vitamin D is a steroid which is formed by skin and it regulate the expression of various genes. Since both Vitamin D and thyroid hormones act via steroid receptors; so any alteration in the level of Vitamin D is possible to increase problems related with hypothyroidism. The association studies between Vitamin D insufficiency and primary hypothyroidism have given mixed results. MATERIAL AND METHODS: this study was conducted in Rama Medical College. The study was conducted for duration of six month. This cross sectional study enrolled 100 subjects. Under absolute aseptic circumstances venous blood was drawn from anticubital vein. Levels of T3, T4 and TSH were estimated with the use of fluorescence array. To determine the levels of Vitamin D, 25(OH)D was calculated. All the data was set in a tabulated form and analyzed using SPSS software. Independent T Test was used for comparison. RESULT: At the study baseline, we engaged 230 members; though, 30 patients were excluded from the study because of not fulfilling the inclusion criteria. In the current study,200 patients(n = 100) and placebo (n = 100)] in our study 59% patients have deficiency of vitamin D 21% patients shows insufficient in vitamin D .20%patients had sufficient level of vitamin D. There was a major disparity in the level of Vitamin D in all the cases. CONCLUSION: Overall, the current study demonstrated that vitamin D have quite important relation with the hypothyroidism
Authors and Affiliations
Md Rashid Taj, Khalda Nasreen
Keywords
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