Saliva as a diagnostic sample of SARS-CoV-2: an integrative review
Journal Title: Revista Uningá - Year 2022, Vol 59, Issue 1
Abstract
In March 2020, the disease caused by the new coronavirus (SARS-CoV-2) was characterized as a pandemic. Due to the magnitude that the disease has reached and its unprecedented character, a growing scientific interest in the disease has emerged, with searches to find new diagnostic methods, increasing the speed to obtain test results and, consequently, a better epidemiological mapping of the disease. This integrative review aims to analyze the main scientific evidence on the use of saliva as a diagnostic method for COVID-19. In the present integrative review, searches were conducted in four electronic databases in March 2022, namely: PubMed, in which results were included exclusively in English, and in the platforms Google Scholar, SciELO and Virtual Health Library (VHL), with the inclusion of results strictly in Portuguese. Different keywords were used according to the dominant language of the databases, being in PubMed in English language chosen ''SARS-CoV-2'', ''saliva'', ''diagnosis'', ''viral load'' and ''coronavirus COVID-19'' and in the other platforms, in Portuguese language ''saliva'', ''covid'' and ''diagnosis''. Among the 45 articles included and analyzed, more than half classified saliva as an alternative or complementary diagnostic method. Yet, only three articles out of the total number classified saliva as an unviable sample for diagnostic testing. Thus, saliva showed positive results as a diagnostic option and for COVID-19 follow-up and monitoring. However, despite the limitations of the studies, the saliva sample in pediatric patients suggests having low sensitivity.
Authors and Affiliations
Bruna de Paula Nogueira, Bernardo da Fonseca Orcina, Rodrigo Cardoso de Oliveira, Paulo Sérgio da Silva Santos.
Keywords
Related Articles
- EP ID EP711883
- DOI doi.org/10.46311/2318-0579.59.eUJ4358
- Views 106
- Downloads 0
Lactose content in powdered milk and/or milk compound lactose-free
Lactose is a disaccharide formed by glucose and galactose. Individuals with deficiency or absence of the enzyme responsible for the digestion of the lactose, “lactase”, are diagnosed as “lactose intolerant”. The marketpl...
Hospital morbidity and mortality of malignant neoplasms of the lip, oral cavity and pharynx in Brazil (2016-2021)
The aim of this study was to describe the morbidity and hospital mortality of malignant neoplasms of the lip, oral cavity and pharynx in Brazil (from 2016 to 2021). This is an epidemiological, observational, analytical a...
Being family of mental health consumers: experiences and feelings
To know the experiences of care of family members of mental health users who are accompanied in a Psychosocial Care Center II in the southern region of the country. This is an exploratory and descriptive research with a...
Implications of vitamin D insufficiency/deficiency in autoimmune diseases: A review
Vitamin D is a fat-soluble steroid hormone with a wide range of biological effects that go beyond the regulation of calcium metabolism and bone health, reaching a preponderant role in maintaining systemic homeostasis, re...
Knowledge and precautions of light-curing composite resin restorations by dental students
Composite resin is versatile material for performing several dental procedures in dentistry, and its use has already been consolidated in this field. The clinical success of adhesive restorations is directly related to t...