Salivary Alkaline Phosphatase, Calcium and Phosphorous as Biochemical Markers in Chronic Periodontal Disease
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 3
Abstract
Background: Alkaline phosphatase (ALP), Calcium and Phosphorous are biomarkers used in inflammatory diseases of the hard and soft tissue and they can serve as a useful tool to measure the efficacy of the non-surgical periodontal therapy. Objectives: this study aimed to determine the salivary alkaline phosphatase activity, salivary calcium and phosphorous in chronic periodontitis before and after the oral hygiene improvement, scaling, and root planning. Materials and methods: Forty subjects were selected from UQUDENT teaching hospital and classified into 2 groups: Group 1 (20 adult healthy subjects), Group 2 (20 adult chronic periodontitis patients). Saliva was collected from each case for determination of alkaline phosphatase activity, salivary calcium and phosphorous spectrophotometrically using commercial kits before and after patients receive periodontal treatment. Results: The salivary calcium and phosphorous levels were higher but non-significant in healthy subject than chronic periodontitis patients before treatment. The calcium level is significantly increased after treatment, while phosphorous level is non-significantly decreased after treatment. Alkaline phosphatase activity is significantly decreased in chronic Periodontitis patients before the treatment compared with the healthy subjects and is significantly decreased in chronic periodontitis after treatment than before treatment. Conclusion: It could be concluded that increase in the salivary alkaline phosphatase level and decreased salivary calcium level in chronic periodontitis may be considered as biochemical markers for the detection and progression of periodontal disease.
Authors and Affiliations
Amjad Alaauldeen, Fathy Elfasakhany, Amal Al-Deeb
Keywords
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- EP ID EP531408
- DOI 10.21276/ijmrp.2018.4.3.003
- Views 89
- Downloads 0
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