Sarilumab:A New Arsenal for Rheumatoid Arthritis
Journal Title: International Journal of Medical and Dental Sciences - Year 2017, Vol 6, Issue 2
Abstract
Rheumatoid arthritis is a debilitating disease that has significant impact on quality of life. Biological and non biological DMARDs improved the outcome in RA patients. New agents are still required in inadequate responders or intolerant patients. FDA has recently approved a new drug Sarilumab, a monoclonal antibody for the treatment of moderate to severe form of RA which acts by binding to Interleukin receptor 6 and interrupts the resultant cytokine-mediated inflammatory signaling.
Macrodystrophia Lipomatosis:A Case Report
Macrodystrophia Lipomatosa is a rare cause of congenital macrodactyly characterized by progressive proliferation of all mesenchymal elements, with disproportionate increase in fibroadipose tissue. This anomaly is reporte...
Validation of Two Rapid Serological Tests for Human Brucellosis Detection
As brucellosis have several non-specific clinical phases, the search for reliable diagnosis of the disease is necessary. Therefore, for serological determination of brucellosis, rapid immunofiltration tests designated as...
A Drug Utilisation Study of Antihyperglycaemic Agents in a Rural Tertiary Care Hospital
Background: Diabetes mellitus is an emerging non communicable, life style disease. The aim was to evaluate the drug utilization pattern of anti-diabetic drugs in diabetic outpatients and monitor the adverse drug reaction...
Maxillofacial Injuries Due to Road Traffic Accidents in Saudi Arabia: A Review of Incidence, Demographic Factors & Prevention Strategies
Background: World Health Organization has estimated that nearly 25% of all injuries fatalities worldwide are a result of road traffic crashes with 90% of the fatalities occurring in low and middle income countries. Traum...
Prevalence of Anemia and Micronutrient Deficiency in Elderly
Background:Untreated geriatric anemia is important to diagnose early as it is associated with greater morbidity and mortality in comparison to the anemia in younger adults.Objectives:To determine the prevale...