Schizophrenia and Its Treatment: An Overview
Journal Title: International Journal of Pharmaceutical Science Invention - Year 2018, Vol 7, Issue 3
Abstract
We discuss the schizophrenia disease and possible model to understand precise mechanism of antipsychotic drugs. The symptoms of schizophrenia disorder have three major categories: positive, negative and cognitive Positive symptoms include auditory and visual hallucinations, delusions, conceptual disorganization and thought disorder. Negative symptoms are associated with emotional blunting, social withdrawal, anhedonia, avolition, poverty of thought and content of speech. While, cognitive symptoms include impaired executive function, working memory and attention. Available antipsychotic are divided in to two categories i.e., first generation antipsychotic drugs (typical antipsychotic drugs) and second generation antipsychotic drugs (atypical anti psychotic drugs). All current antipsychotics function primarily by blocking dopamine receptors. Present scenario revealed that atypical antipsychotic drugs are widely prescribed for psychotic disorders as compared to typical antipsychotic drugs.
Authors and Affiliations
Umesh Kumar, Pavan Kumar Gautam, Naveen Khatak, Seema Kumari
Keywords
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