Screening for Acanthosis Nigricans in Type 2 Diabetes Mellitus - It’s Time for Reinforcement
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2018, Vol 6, Issue 2
Abstract
Background: Acanthosis nigricans is a well-known external marker for insulin resistance, obesity and type 2 diabetes mellitus (T2DM). The prevalence of acanthosis varies among different ethnic groups. Aim: The aim of the study was to study the prevalence and relationship of acanthosis nigricans with age, body mass index (BMI), and other risk factors in T2DM. Methods: A total of 300 patients with T2DM attending the medical outpatient department in a tertiary care teaching hospital were included in the study. Their demographic and clinical parameters were recorded. The presence of acanthosis nigricans, its severity and relationship with other diabetic risk factors were assessed. Results: Among the 300 patients enrolled in study 187 patients had evidence of acanthosis of varied severity. 172 were female patients. The mean BMI was 28.8 kg/sq m and mean waist circumference was 97.5 cm. Significant association (P < 0.005) of acanthosis nigricans was noted with younger age, female sex, overweight, and obesity. Similar significance was also noted with hypertension and dyslipidemia. However, the duration of T2DM, previous history of CVA or coronary artery disease, family history of T2DM did not bear a significant association with the presence of acanthosis. Conclusion: The high prevalence of acanthosis nigricans in T2DM patients favors it as a potential screening tool in the T2DM risk assessment.
Authors and Affiliations
Swathy Moorthy, M K Sudhakar
Keywords
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