Abstract

In the present study, an attempt was taken to determine the analgesic activity of methanolic extract of Hypnea flagelliformis Greville ex J.Ag. in Koothankuzhi coast, Tamil Nadu, India. Methods: The dried powdered Hypnea flagelliformis Greville ex J.Ag. was extracted in absolute methanol to estimate the analgesic activity. The analgesic activity was predicted on intact rats by tail flick latency in tail immersion method. Diclofenac Sodium in the dose of 100mg/kg was used as standard drug. Methanolic extracts of Hypnea flagelliformis Greville ex J.Ag. were given in the doses of 200 and 400mg/kg. Control group received normal saline solution. All the doses administered orally. Results: Results showed that both the doses of methanolic extracts of Hypnea flagelliformis Greville ex J.Ag. had analgesic activity. Conclusion: From the results, it was concluded that methanolic extract of Hypnea flagelliformis Greville ex J.Ag. at 400mg/kg was found to have more effect as compared to 200mg/kg methanolic extract.

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