Screening of Antimicrobial activity of Guduchi Ghana (dried aqueous extract of Tinospora cordifolia (Willd.) Miers)
Journal Title: Journal of Ayurvedic and Herbal Medicine - Year 2016, Vol 2, Issue 6
Abstract
Guduchi (Tinospora cordifolia (Willd.) Miers) is one of the most versatile rejuvenating herbs, possessing numerous therapeutic attributes. Recent reports investigated and ascertained its role as a potent antimicrobial herb. No published reports on antimicrobial profile of its dosage form- Guduchi Ghana are available till date. Present study was therefore attempted to evaluate comparative antimicrobial efficacies of Guduchi Ghana prepared by two different methods – (i) classical Ayurvedic method and (ii) modified method. Recommended microbial strain like; Salmonella typhi, Escherichia coli, P. aeruginosa and Staphylococcus aureus were used in this study for the same purpose. Both samples showed significant antibacterial activity and possess great potential against microorganisms, where Guduchi Ghana prepared by classical method showed better results. Physicochemical analysis showed insignificant difference between samples. Phytochemical analysis for various functional groups revealed the presence of glycosides, alkaloids, tannins, phenols, starch and sterols in both samples, which might be accountable for their antimicrobial potential. No microbial load was detected within both samples. The results also validate the traditional uses of Guduchi in various skin ailments. Present study may prove a torch bearer for future studies to understand its biological activities.
Authors and Affiliations
Rohit Sharma, PK Prajapati
Keywords
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