SENSITIVITY STATUS OF MYCOBACTERUM TUBERCULOSIS COMPLEX STRAINS ISOLATED IN OUR CLINIC TO ANTITUBERCULOSIS DRUGS
Journal Title: Kocatepe Medical Journal - Year 2021, Vol 6, Issue 22
Abstract
OBJECTIVE: Tuberculosis (TB) is a chronic infectious disease caused by microorganisms belonging to the Mycobacterium tuberculosis complex (MTBK) group. This disease is treated and controlled with antituberculosis drugs; but sometimes it may not respond to medications. Investigation of drug resistance in tuberculosis, forms the basis of tuberculosis control and treatment programs. MATERIAL AND METHODS: In our study, it was aimed to investigate the susceptibility of MTBK isolate, isolated in our laboratory to primary antituberculosis drugs and to determine their resistance patterns. Between 2011 and 2019, 8804 clinical samples sent to the microbiology laboratory with the suspicion of tuberculosis were evaluated in our clinic. RESULTS: Tuberculosis culture was positive in 126 of the samples included in the study. Anti-tuberculosis susceptibility test was applied to 126 samples (1.4%). 28 (22.3%) isolates were found to be resistant to at least one of the tested antituberculosis drugs tested. Multidrug resistance was found at the rate of 2.38%. CONCLUSIONS: In order to prevent the development of resistance in the treatment of tuberculosis and to provide a healthy treatment, culture and antibiotic sensitivity tests should be performed for each patient and data should be obtained.
Authors and Affiliations
Aydın BALCI, Ersin GÜNAY,Cengiz DEMİR, Şule ÇİLEKAR, İbrahim Güven COŞĞUN, Suphi AYDIN
Keywords
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- EP ID EP697204
- DOI https://doi.org/10.18229/kocatepetip.802182
- Views 107
- Downloads 0
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