Sensorineural hearing loss (SNHL) and ophthalmic complications as a cause of congenital cytomegalovirus (CMV) infection in children
Journal Title: Annales Academiae Medicae Silesiensis - Year 2014, Vol 68, Issue 3
Abstract
INTRODUCTION Congenital cytomegalovirus (CMV) infection is a cause of sensorineural hearing loss (SNHL) in children. Symptomatic CVM is present in 5–10% of children with this disease and typical clinical signs of congenital cytomegalovirus infection are: microcephalia, mental retardation, progressive major amblyacousia, neuromuscular infection and ocular complications. One percent of live births has cytomegalovirus infection, 90% neonates with perinatal infection do not show symptoms of the disease. It is believed that symptomatic CMV is associated with a 90 % risk of neurological sequelae including hearing loss, or a risk of ophthalmic disorders. Ophthalmological symptoms of congenital CMV infection may affect between 5% and 30% of children. Most are disorders of the posterior segment of the eye such as retinochorioiditis, macular scars and peripheral retina, optic nerve atrophy and uveitis. Pathology of the anterior segment of the eye exists in the form of congenital cataract and corneal scarring. It is believed that with congenital CMV infection, strabismus, microphthalmia or lack of eyeball may coexist. Hypoacusis occurs in 30–60% of children with congenital symptomatic CVM. . The aim of the paper is to present the audiological examination schema in our Clinic for patients with CMV infection, involving the tonal audiometry threshold and objective hearing organ testing, as well as the ophthalmological view on these infections. MATERIAL AND METHOD The study group consisted of 30 children with cytomegalovirus infection at the age of 2–12 years, hospitalized at the Instytucie Centrum Zdrowia Matki Polki (Institute of Polish Mother's Health Center) in Lodz. 22 of them (73%) had congenital cytomegalovirus, 8 (27%) acquired cytomegalovirus. RESULTS AND DISCUSSION In the cases of congenital CMV infection, half of the patients in our study had bilateral profound sensorineural hearing loss (in pure tone audiometry threshold curves of air and bone conduction at low and medium frequencies of 70 dB, while for frequencies above 2000 Hz at 90 dB). The presence of wave V in the ABR examination was recorded on both sides at the level of 90 dB. Bilateral sensorineural hearing losses were associated with mental and physically retardation, brain malformation and microcephalia. In the group of children with acquired CMV, we did not observe hearing loss. CONCLUSIONS This research proved that only congenital cytomegalovirus infection caused hearing loss. In spite of this, all children with congenital and acquired CMV should be consistently controlled by an audiologist and ophthalmologist.
Authors and Affiliations
Małgorzata Śmiechura, Łukasz Konopka, Wiesław Konopka
Keywords
Related Articles
- EP ID EP375734
- DOI -
- Views 87
- Downloads 0
Związek pomiędzy chorobą nowotworową a alergią atopową
WSTĘP: Ochronny lub stymulujący wpływ atopii na ryzyko rozwoju nowotworu pozostaje otwartym pytaniem. Dotychczasowe prace naukowe analizujące temat przynoszą różne odpowiedzi. W pracy badano występowanie chorób nowotworo...
Large cerebello-pontine angle tumor in pregnancy – case report
A large cerebello-pontine angle tumor in pregnancy is a rare illness which is a challenge for neurosurgeons, obstetricians and anesthesiologists. The urgent treatment of the life-threatening obstructive hydrocephalus has...
V Międzynarodowa Konferencja Europejskiej Platformy Medycyny Fotodynamicznej
W dniach 7–9 listopada 2013 r. w Ustroniu odbyły się 5. Międzynarodowa Kon-ferencja Europejskiej Platformy Medycyny Fotodynamicznej (5th International Meeting of the European Platform for Photodynamic Medicine, EPPM) ora...
The effect of hemodialysis on glycemic variability
The steady increase in the incidence of type 2 diabetes, which is the leading cause of end-stage renal failure among hemodialysis patients, has been the subject of multidisciplinary research. Much attention has been devo...
The incidence of adverse reactions to cosmetics in students of the Medical University of Silesia in Katowice
INTRODUCTION The objective of this study was to determine the rate of adverse reactions to cosmetics among female students of the Medical University of Silesia in Katowice and to determine the type of disorders and cosme...