Sequel of Ring Enhanced Lesion on Computerized Tomographic Scans of Brain of Patients Presenting with Seizure
Journal Title: Nepal Journal of Neuroscience - Year 2009, Vol 6, Issue 1
Abstract
A seizure for the first time in life with ring enhanced lesion (REL) in computerized tomographic (CT) scan is not an uncommon problem in a developing country. Only few studies have been done to assess the sequel of neurocysticercosis (NCC) presenting as REL on CT scan and even fewer studies to determine the duration of anti epileptic drug (AED) to be given in such patients with seizure. This prospective,non-randomisede,non-controlled clinical trial was undertaken to find out the sequel of NCC. We also aimed to find out whether AED needs to be continued irrespective of the sequel of the REL. All the patients presenting with seizure due to REL on CT scan were shortlisted. Follow up was done for at least a year, from March 2007 to March 2008, after putting the patients on AED. 42 patients (21 males and 21 females) were finally short listed and followed up.Most of the patients were between 20 to 40 years of age. REL disappeared in 6 (14.2%), persisted in 3 (7.1%), and calcification occurred in the majority ,ie 33( 78.6%).Only 9 patients could be taken off the AED as they became seizure-free on stopping the AED. The majority of the patients, i.e., 33 (79%) had to continue AED. Most REL (NCC) on CT scan calcify and may need long term AED. Seizure due to NCC is a serious and a common cause of morbidity. A population based study is urgently needed.
Authors and Affiliations
Rabindra Shrestha, MD
Keywords
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