Seroprevalance of Hepatitis B Surface Antigen amongst general population in a Tertiary Care Hospital
Journal Title: Indian Journal of Microbiology Research - Year 2016, Vol 3, Issue 4
Abstract
Hepatitis B virus (HBV) is a DNA virus belonging to Hepadnaviridae family.1,2 HBV infection leads to a wide range of liver diseases from acute hepatitis to chronic hepatitis, cirrhosis, and hepatocellular carcinoma (HCC).2 World Health Organization (WHO) has classified HBV prevalence into high endemicity (>8%), intermediate (2-7%) and low endemicity (<2%). HBV prevalence in India is in intermediate range. Every year 100,000 Indians die due to HBV infection related illnesses.3 The diagnosis of HBV infection is based on a group of clinical, biochemical, histological, and serological markers. Interpretation of clinical significance of HBV markers and their relevance to the management of HBV infection is helpful to clinicians for appropriate therapy. It is particularly important for physicians to screen for HBV infection in HBV-endemic areas and to monitor liver disease progression in HBV carriers by using both serological and virological markers, so that effective treatment can be initiated early before the development of advanced liver disease.
Authors and Affiliations
Gitanjali Badave, Neelima Pantagada, P. Nageswara Rao
Keywords
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