Seroprevalence and Recent Trends of Dengue in a Rural Area in South India
Journal Title: International Journal of Current Microbiology and Applied Sciences (IJCMAS) - Year 2017, Vol 6, Issue 1
Abstract
Dengue is the most critical arthropod borne viral infection and a major public health concern globally in recent years infecting about 50 million people each year. Dengue infected patients present with symptoms varying from mild fever to life threatening shock. Associated thrombo cytopaenia is a hall mark of a life threatening dengue infection. A platelet count of less than 100,000/µl is a diagnostic criteria for dengue haemorrhagic fever (DHF) as per World Health Organization (WHO) guidelines, 2015. Thrombocytopaenia can be seen in both dengue fever (DF) and DHF. In this study, a total of 1228 patients both out patients and inpatients of Akash Hospital in Bengaluru rural were screened for dengue infection. A rapid-Immuno chromatographic test, (ICT) SD Bioline Dengue Duo® was used to run all the samples for detection of NS1antigen (nonstructural protein), IgM (immunoglobulin M) and IgG (immunoglobulin G). NS1 antigen is an early diagnostic marker, appears on the first day of fever. All positives were confirmed by using Bhat Bioscan® Dengue rapid test kit also detects NS1antigen, IgM and IgG. Out of 1228 samples 324 samples were seropositive. Platelet counts were performed on whole blood on these seropositive patients using Sysmex XS 800i automated haematology analyser. Among the 324 seropositive patients, 17(5.24%) had severe thrombocytopaenia, 109 (33.64%) were showing moderately low platelet count, 93(28.70%) with a borderline count and 105 (32.40%) had a normal platelet count.
Authors and Affiliations
Ruby Thomas
Keywords
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- EP ID EP566328
- DOI 10.20546/ijcmas.2017.601.005
- Views 43
- Downloads 0
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