Seroprevalence of HCV infection among patients at a tertiary care center in Eastern India- Urgent need to implement strategies to interrupt HCV transmission and develop HCV vaccine for the susceptible population.
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 7
Abstract
Since health-care workers (HCW) are exposed to occupational blood contact and subsequently are at risk to infection with blood borne pathogens from an infected patient, therefore, in a healthcare setup , a preliminary screening is done before performing any minor or major invasive procedure, to rule out the presence of HBV, HIV and HCV infection in patients. To protect a HCW in cases of accidental exposure to HIV positive sera, antiretroviral drugs given as post exposure prophylaxis (PEP) is available for HBV, a safe and effective vaccine is available but for HCV, no such vaccine is available till date. Since the transmission of HCV to HCW also depends on the seroprevalence of HCV infection in the local population, we decided to do a study to find the seroprevalence of HCV infection in patients attending various OPD and IPD of a tertiary care center of Eastern Bihar. A retrospective study from June 2017 to June 2018 was carried out in the virology lab of the tertiary care center of Eastern India in which records of all patients whose sera was screened for detection of Anti HCV antibody by Benesphera Microwell ELISA (IHF) were obtained and analyzed . A total of 37845 samples were screened during the above mentioned period out of which 142 (0.37% ) were found to be positive fo HCV antibodies . Out of 142 seropositive patients, 65 ( 45.77 %) were male and 77 ( 54.22%) were females. The seroprevalence of HCV infection in this region of eastern India indicates an urgent need to implement strategies to interrupt HCV transmission and develop HCV vaccine for the susceptible population.
Authors and Affiliations
Dr. Nidhi Prasad
Keywords
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