Seroprevalence of hepatitis B virus, hepatitis C virus and human immunodeficiency virus in the western region of Nepal
Journal Title: Journal of Advances in Internal Medicine - Year 2016, Vol 5, Issue 1
Abstract
Background and aims: The hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV) are associated with major public health concerns. The aim of the study was to determine the seroprevalence of HBV, HCV and HIV in the western region of Nepal. Methods: This was a cross-sectional observational study, in which 15,791 patients, attending to Manipal Teaching Hospital, Pokhara, Nepal, were investigated for HBV, HCV and HIV from June 2013 to March 2016; demographic and biochemical profile were studied among the patients with positive test results. Results: Among 15,791 patients [male 6614 (41.9%) and female 9177 (58.1%)], HBV was found in 180 (1.1%), HCV in 52 (0.3%) and HIV in 77 (0.5%). The HBV was found in 63.9% of males and 36.1% of females, HCV in 67.3% of males and 32.7% of females, and HIV in 61% of males and 39% of females which showed that males had more positivity of HBV (P<0.001), HCV (P<0.001) and HIV (P 0.001) than that of female. The HBV was found more in 20-29 years age group (27.2%), HCV in 30-39 years (32.7%), and HIV in 40-49 years (28.6%), with all having p<0.001. Among the patients of HBV, HCV and HIV, the mean values of total bilirubin were 1.4 mg/dl, 0.8 mg/dl and 2.6 mg/dl, Aspartate Transaminase 75.9 U/L, 54.3 U/L and 92.7 U/L, Alanine Transaminase 54.6 U/L, 55.5 U/L and 56.1 U/L, and Alkaline Phosphatase 124.2 U/L, 109.2 U/L and 107.2 U/L, respectively. The majority of patients with HCV had a history of intravenous drug abuse and HIV had concomitant alcoholic liver disease. Conclusion: The HBV was more prevalent followed by HIV and HCV in the western region of Nepal with more prevalence seen in males than in females. Regular screening of HBV, HCV and HIV among the selected patients can help detecting many new cases in Nepal.
Authors and Affiliations
Umid Kumar Shrestha*| Manipal College of Medical Sciences, Pokhara, Nepal, Bhup Dev Bhatta| Manipal College of Medical Sciences, Pokhara, Nepal
Keywords
Related Articles
- EP ID EP4802
- DOI http://dx.doi.org/10.3126/jaim.v5i1.17064
- Views 455
- Downloads 20
EFFECT OF ORGANIC AND INORGANIC SOURCES OF NITROGEN ON GROWTH AND YIELD COMPONENTS OF MAIZE (ZEA MAYS L.)
A field experiment was carried out to study growth and yield response of maize (Zea mays L.) to organic and inorganic sources of nitrogen . Two maize varieties namely Azad-22 and Azad-28 were fertilized with farm yard ma...
IN VITRO SELECTION FOR SALT TOLERANCE IN LENTIL (LENS CULINARIS MEDIK)
While plant breeding methods have been diverted toward improve of real crop yield in drought and salinity conditions, the achievement of plant cell culture and regeneration of plants from mutant cells is increasingly i...
THE EFFECT OF ROTOTILLER EQUIPPED WITH SERRATED BLADES ON SOME SOIL PROPERTIES
Experiments were conducted in a silty clay soil to evaluate the performance of a rototiller equipped with new serrated blades. Tests were conducted at tractor forward speeds of 1.0, 1.5 and 2.0 km/h and rotational speeds...
ALLELOPATHIC EFFECTS OF ANACARDIUM OCCIDENTALE LINN OF TERENGGANU AND KELANTAN ON GROWTH OF MAIZE AND CUCUMBER
A study was conducted on Anacardium occidentale Linn. (Cashew) from Terengganu and Kelantan states of Malaysia, with the aim to determine the allelopathic effects of leaf and root extracts on the growth of bioassay plant...
Insulin Resistance in firstborn offspring of mother who developed diabetes later in fourth decade: Are both related to possible maternal malnutrition?
Back grounds and Aims: Diabetes mellitus is increasing each day. We aimed to study the insulin resistance (IR) in the offspring of people with diabetes and its relation with lifestyle and clinical factors. Methods: This...