Seroprevalence of Human Immunodeficiency Virus (HIV), Hepatitis B Virus (HBV), Hepatitis C Virus (HCV) and Syphilis among Voluntary Blood Donors in Rural Southwestern Uganda: A Retrospective Study
Journal Title: International Journal of TROPICAL DISEASE & Health - Year 2017, Vol 24, Issue 3
Abstract
Despite the improvement with blood screening, transfusion transmissible infectious (TTIs) agents such as human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV) and syphilis are still among some of the challenges in the blood safety for the recipient in Uganda. The aim of this study was to determine the prevalence of the four TTIs among the voluntary blood donors in southwestern Uganda. A retrospective study was conducted using one year data (January 2014 to December 2014) from a regional blood bank in southwestern Uganda. Routine screening by the blood bank included anti HIV, hepatitis B surface antigen, anti-hepatitis C using the Abbott ARCHITECT i2000 SR analyzer. Both Rapid Plasma Reagin (RPR) test and Treponema Pallidun Haeagglutination (TPHA) tests were used for detection of syphilitic infection. 5.67% of blood donors were positive for any of the screening tests and 0.34% had multiple infections. The overall seroprevalence was 1.03%, 1.87%, 2.22%, and 0.54% for HIV, HBV, HCV and syphilis respectively. The most common dual combinations were HBV-HCV 51.8 %, HIV-HCV 22.7% and HIV-HBV 10.0%. Triple infection with HIV-HBV-HCV was 3.7% and HIV- HBV-Syphilis was 1.3%. There were no quadruple infections detected in this study. There was statistically significant increase of HIV seropositivity among the age group of donors above 47 years (p=0.001). A substantial prevalence of TTIs was found among the blood donors in southwestern Uganda.
Authors and Affiliations
Richard Onyuthi Apecu, Edgar M. Mulogo, Fred Bagenda, Andrew Byamungu, Yap Boum II, Joel Bazira, Frederic Byarugaba
Keywords
Related Articles
- EP ID EP312663
- DOI 10.9734/IJTDH/2017/34605
- Views 63
- Downloads 0
Hematological Changes among Sudanese Patients with Acute Viral Hepatitis B
Background: Viral hepatitis B is a common cause of liver disease with considerable morbidity and mortality throughout the world. As the liver is responsible for producing many haemopoietic factors and performs many criti...
First Record of Indigenous Furuncular Myiasis Due to Cordylobia anthropophaga in Unusual Ecologic Niche, Makkah, Saudi Arabia
Background: Cordylobia anthropophaga, one of the known furuncular myiasis-associated fly, has long been limited to the Afro-tropical region. In Saudi Arabia, Southwest region, part of the Afro-tropical region, has been c...
Ectopic Pregnancy: Recent Experience in a Tertiary Hospital, South-Southern Nigeria
Objective: To assess the incidence, clinical presentation, management and associated morbidity of ectopic pregnancy in a tertiary health institution in South-southern Nigeria over a 2-year period. Methods: Hospital-based...
Some Haematological Parameters and Immunoglobulin Levels in Mycobacterium tuberculosis Infected Patients in Benin City, Southern Nigeria
Mycobacterium tuberculosis (MTB) infection is a major public health challenge in Nigeria. This research aims at determining the effect of MTB infections on some haematological and immunological parameters in MTB patients...
Differentials and Correlates of Infants Mortality in Nigeria: A Comparative Survival Analysis between North East and South West Nigeria
Aims: Infant mortality rate (IMR) is not only used as a demographic measure, but also as an important health indicator of a society as well as a measure of its living standard worldwide. The Nigeria Demographic and House...