SEROPREVALENCE OF PARVOVIRUS B19 AMONG SUDANESE PATIENTS WITH SYSTEMIC LUPUS ERYTHMATOSUS
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2014, Vol 3, Issue 4
Abstract
Background Parvovirus B19 is a human pathogen that may result in spectrum of clinical features range from subclinical infection to potentially fatal effects. To the best of our knowledge, there was no study published in open literature regarding the coexistence of Parvovirus B19 with systemic lupus erythmatosus (SLE) among Sudanese. The aim of this study was to determine the seroprevalence of parvovirus B19 among patients with SLE in Khartoum state-Sudan. Methods: it was descriptive, cross sectional study. 90 blood samples were collected from known Sudanese patients with systemic lupus erythmatosus disease living Khartoum state in the period between April and July 2014. ELISA technique was used for detection of IgG and IgM against Parvovirus B19 in patients' serum. Result: The result showed that 56.7% of SLE patients were possessing antibodies to parvovirus B12, the IgG was detected in 49% while 30% of the patients had IgM. Conclusion: Parvovirus B19 infection was frequent among patients with SLE, especially in the age group between 15-25 years. We recommended the rheumatologist to investigate their SLE patients for parvovirus B19 routinely to improve the patients health since the SLE symptoms will obscure the infection with parvovirus B19 and miss diagnosis may occur.
Authors and Affiliations
Mohammed J. El-Mak| Microbiology Department, Faculty of Medical Laboratory Sciences, Al-Neelain University, Sudan, Mohammed Abbas| Medical Laboratory Department, College of Applied Medical Sciences, Salman bin Abdulaziz University, Saudi Arabia., Mohammed I. ELsedig| Microbiology Department, Faculty of Medical Laboratory Sciences, Karrary University, Sudan, Khalid Enan| Microbiology Department, Faculty of Medical Laboratory Sciences, Al-Neelain University, Sudan
Keywords
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