Serotype-Specific Pneumococcal Status prior to PCV 13 Administration in Children and Adolescents with Inflammatory Bowel Disease
Journal Title: Polish Journal of Microbiology - Year 2016, Vol 65, Issue 1
Abstract
The aim of this study was to evaluate the serotype-specific pneumococcal status of children and adolescents with inflammatory bowel disease (IBD) who were naïve to pneumococcal vaccination before administering the 13-valent pneumococcal conjugate vaccine (PCV 13). This was an open, prospective study on children and adolescents aged 5–18 years who had IBD and were naïve to pneumococcal vaccination. A single dose of PCV 13 was administered to each patient. The geometric mean concentrations (GMCs) were measured for all 13 serotypes. A total of 122 subjects completed the study. Prevaccination GMCs ranged from 0.55 μg/ml (serotype 4) to 4.26 μg/ml (serotype 19A). Prior to the administration of PCV 13, high GMCs were detected in older children and adolescents who had IBD and were naïve to pneumococcal vaccination.
Authors and Affiliations
Aleksandra Banaszkiewicz, Brygida Targonska, KInga Kowalska-Duplaga, Katarzyna Karolewska-Bochenek, Agnieszka Sieczkowska, Urszula Grzybowska-Chlebowczyk, Elzbieta Krzesiek, Izabella Lazowska-Przeorek, Maria Kotowska, Edyta Sienkiewicz, Jaroslaw Walkowiak, Hanna Gregorek, Andrzej Radzikowski, Piotr Albrecht
Keywords
Related Articles
- EP ID EP81096
- DOI -
- Views 85
- Downloads 0
Bacterial Diversity and Abundance in Shell Biofilms from the Freshwater Snail Pleurocera canaliculatum (Cerithioidea: Pleuroceridae)
Mollusk shells provide a hard substrate for aquatic biofilm colonization. While most work has focused on bivalve shells and grazing, little work has focused on gastropod shells and the microbes growing on them. We s...
Characterization of Endolithic Culturable Microbial Communities in Carbonate Rocks from a Typical Karst Canyon in Guizhou (China)
The endolithic environment is a ubiquitous habitat for microorganisms and a critical interface between biology and geology. In this study, a culture-based method and the phylogenetic analysis based on 16S rRNA and intern...
Evaluation of Two Lactic Acid Bacteria Starter Cultures for the Fermentation of Natural Black Table Olives (Olea europaea L cv Kalamon)
The production of Greek-style natural black table olives remains an empirical process relying on spontaneous fermentation despite its economic significance. For this reason producers often resort to increased NaCl concen...
<strong>Sulphate Reducing Activity Detected in Soil Samples From Antarctica, Ecology Glacier Forefield, King George Island</strong>
We determined sulphate-reducing activities in media inoculated with soils and with kettle lake sediments in order to investigate their potential in geomicrobiological processes in low-temperature, terrestrial maritime An...
Recovery of Gram-Positive Cocci and Candida albicans from Peroxygens/Silver-Based Disinfectants
Neutralization method evaluation is an important first step in disinfectant validation study program. It is, also, crucial in the assessment of the efficiency of microbial recovery media in the presence of residual bioci...