Serum Bilirubin and C-Reactive Protein as Predictor of Perforation in Acute Appendicitis- A Prospective Cohort Study
Journal Title: IJSR-International Journal Of Scientific Research - Year 2016, Vol 5, Issue 11
Abstract
Introduction- Acute appendicitis is a common surgical emergency, further complicated by gangrene, perforation and diffuse peritonitis. An early diagnosis and treatment of perforated appendix can decrease cost as well as morbidity associated with the disease. Total Serum Bilirubin (TSB) and C-reactive protein (CRP) can be potential markers to predict perforation in patients with acute appendicitis. Method- TSB and CRP were measured in patients with acute appendicitis. Patients were divided into two groups- group 1 (without appendicular perforation) and group 2 (with appendicular perforation) on the basis of operative findings. Sensitivity, Specificity, Positive predictive value (PPV) and Negative predictive value (NPV) were calculated for both parameters. Results- The sensitivity, specificity, PPV and NPV of raised TSB in Group 2 were 86.66%, 65.71%, 72.22% and 92% respectively. The sensitivity, specificity, PPV and NPV for CRP was 80.0%, 54.28%, 38.7%and 84% respectively. TSB was found to be a better marker for diagnosing perforated appendix than CRP. Conclusion- Both TSB and CRP are useful markers for early diagnosis of perforated appendix, with TSB being better than CRP. But, the present study has a limitation with respect to sample size.
Authors and Affiliations
Dr. Shahab Faria Shahabuddin, Dr. Shehtaj Khan, Dr. Rafiul Imad Finan, Prof. M. Amanullah Khan
Keywords
Related Articles
- EP ID EP344725
- DOI -
- Views 55
- Downloads 0
CORRELATION BETWEEN BLOOD VOLUME AND AMPLITUDE OF QRS COMPLEX IN YOUNG HEALTHY INDIVIDUALS
Back ground Hemodynamic instability following trauma is perhaps the commonest cause of loss of life. The standard vital signs used to determine hemodynamic status are static measurements rather than dynamic, and may not...
Study of Doppler Scan Parameters for Ovarian Masses
Ovarian mass represents a common problem in clinical practice. Colour Doppler imaging with pulsed Doppler spectral analysis improves the characterization of ovarian masses by means of blood flow measurements obtained fro...
RELATIONSHIP BETWEEN PROCRASTINATION AND EMOTIONAL STRESS OF HIGHER SECONDARY SCHOOL STUDENTS IN KOTTAYAM DISTRICT
The 'Relationship between Procrastination and Emotional Stress of Higher Secondary School Students in Kottayam District' is a descriptive survey study. The sample consist 400 students of a higher secondary school selecte...
MORPHOLOGICAL SPECTRUM OF MALIGNANT RENAL TUMOURS IN DIFFERENT AGE GROUPS - CASE SERIES AND REVIEW OF LITERATURE
Renal tumours have acquired a new face in the recent times due to the expanding list of new entities. Renal cell carcinoma are classified based on their architectural features (eg: papillary RCC ), cytoplasmic features (...
OUTCOME OF FIREARM INJURIES IN TERTIARY CARE IN NORTH INDIA
Gun is favored weapon for assault and defense. Incidence of rearm injuries increasing due to easy availability of arm and ammunition and deterioration of moral values with lack of proper law enforcement. Most of the pat...