Serum C Reactive Protein levels in Stable COPD Patients Attending a Tertiary Care Centre – A Prospective Study
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 8
Abstract
Chronic Obstructive Pulmonary Disease (COPD) is a major cause of morbidity and mortality throughout the world. C-Reactive protein (CRP) is found in blood plasma, which rises in response to inflammation. A prospective study was conducted in a tertiary care teaching hospital to assess the levels of CRP in stable COPD patients. 100 patients with stable COPD without co-morbidities attending the respiratory OPD were recruited. CRP levels were estimated and patients were followed up for a period of 6 months to check CRP levels serially every 2 months. During exacerbation, CRP was estimated and repeated after 2 weeks of remission, if still positive, again repeated after 2 weeks. Average CRP level was high in a significant number of COPD patients. As the stage of COPD advanced CRP levels were also significantly raised. By applying ANOVA test, average CRP between different stages of COPD was found to be significantly high. Even though current smokers and reformed smokers had high average CRP, statistical significance in mean CRP between them and non smokers were not found. There was a negative correlation between CRP & BMI, but was not statistically significant. There was no significant relationship of CRP with age of the patients. There was negative correlation seen with oxygen saturation, with a significant p value. It was concluded that systemic inflammation is inherent to COPD, independent of smoking status, age & BMI but correlates with disease severity
Authors and Affiliations
Dr Sophia Philip
Keywords
Related Articles
- EP ID EP489660
- DOI -
- Views 30
- Downloads 0
Use of Meter Dose Inhaler (MDI) Corticosteroid Therapy, May Cause Tuberculosis, in Patients with Bronchial Asthma
The aim of present study was to evaluate the incidence and pattern of tuberculosis in Bronchial asthma patients receiving inhalational corticosteroid therapy by MDI. Materials and Method: A total of 76 patients taking MD...
Perception of Kshar Sutra Therapy among Medical Interns in Treatment of Piles and Fistula
Large population around the world is suffering from the anorectal disorders especially by piles, fistula and diverse group of pathologic conditions. There conditions are the cause of significant patient discomfort and di...
Study of cytomorphological spectrum of various thyroid lesions and reporting under bethesda system in tertiary care centre
Background: This study has attempted to standardize reporting and cytological criteria in aspiration smears of thyroid swellings with the help of Bethesda System for Reporting Thyroid Cytopathology (TBSRTC). Aims: The ob...
Efficacy of Unweighing System During Over Ground Walking Versus Treadmill Training on Walking Speed in Spastic Diplegic Children
Background: The ability to walk is a major concern of the parents of children with CP, the main problem in spastic diplegia is walking difficulty. Balance disturbance, muscle weakness, spasticity and deformities result i...
Correlation of Demographic Profile and Antibiotic Resistance in Patients with Urinary Tract Infection Attending a Teaching Hospital in Kolkata
The aim of this study was to determine the bacterial aetiology of Urinary Tract Infection (UTI) with their resistance to commonly used antimicrobial drugs and their correlation with age, sex and marital status of the pat...