Serum ferritin level in type 2 diabetes mellitus - A case control study
Journal Title: International Journal of Clinical Biochemistry and Research - Year 2016, Vol 3, Issue 1
Abstract
Background: Hyperferritinemia probably contributes insulin resistance and subsequently to decreased insulin secretion causes for development of insulin resistance. Objectives: Compare HbA1c with Ferritin and find correlation between HbA1c and ferritin in type 2 diabetes mellitus patients, and also to find the best cut-off value for serum ferritin. Material and methods: The study was conducted on type 2 diabetes mellitus patients attended the outpatient department. Totally 99 participants were enrolled for the study, out of which 49 were cases and 50 were age and sex controls. The FBS, PPBS, HbA1c and serum ferritin were estimated. Statistical package for social science software version 19.0 was used for statistical analysis. Results: There statistically significant increase in all the biochemical parameters viz FBS, PPBS, HbA1c and serum ferritin levels in cases compared controls. The p value was 0.0001 for all the parameters, which is highly significant. There was a positive correlation between the HbA1c and Ferritin levels, but it was not statistically significant (r = 0.10). The area under the ROC curve for serum ferritin values at various cut-off was 0.904 and the best cut-off of serum ferritin levels greater than 124ng/ml. Conclusion: Serum ferritin levels were higher in type 2 Diabetes mellitus which positively correlated HbA1c. Thus, routine screening for serum ferritin concentration in diabetes patients can be done to assess the glecemic control in type 2 DM
Authors and Affiliations
Sangappa Virupaxappa Kashinakunti, Kavitha Hiremath, Manjula Rangappa, Gurupadappa Shantappa Kallaganada
Keywords
Related Articles
- EP ID EP242130
- DOI -
- Views 113
- Downloads 0
Comparison of LDL-cholesterol estimated by various formulae with directly measured LDL-cholesterol in a tertiary care centre of Maval Taluka
Introduction Lowdensity Lipoprotein Cholesterol LDLC concentration in blood gives indication of cardiovascular disease risk LDLC may vary at various strata of Triglycerides and in metabolic diseases like Diabetes Mellitu...
Chronic kidney disease among rural population of Muzaffarnagar region
Introduction: Chronic kidney diseases (CKD) comprise the conditions that damage the kidneys and decrease their ability to keep you healthy by doing the jobs listed. If kidney disease gets worse, wastes can build up to hi...
Prevalence of childhood obesity and its determinants among rural children of B G Nagara
Introduction India is witnessing under nutrition as one of the major public health problem however there exists a significant magnitude of overweight and obesity among children and adolescent Childhood obesity has emerge...
Vitamin D Levels and bone mineral density in postmenopausal women
Introduction and Objectives: Osteoporosis characterized by low bone mass is a major health problem in post-menopausal women. Bone Mineral Density (BMD) represents the density or thickness of bones. Vitamin D plays an imp...
A study of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH) in women of Polycystic Ovarian Disease (PCOD) at Tertiary Care Hospital of Gujarat, India
Introduction: Polycystic ovarian disease (PCOS) is one of the most common female endocrine disorders. PCOD produces symptoms in approximately 5% to 10% of women of reproductive age (12–45 years old). It is thought to be...