Vitamin D Levels and bone mineral density in postmenopausal women
Journal Title: International Journal of Clinical Biochemistry and Research - Year 2017, Vol 4, Issue 4
Abstract
Introduction and Objectives: Osteoporosis characterized by low bone mass is a major health problem in post-menopausal women. Bone Mineral Density (BMD) represents the density or thickness of bones. Vitamin D plays an important role in bone growth and maintenance. Vitamin D inadequacy is implicated in the development of osteopenia and osteoporosis. To study the Bone Mineral Density and serum 25-hydroxy Vitamin D levels in post-menopausal women. Materials and Method: This was a cross sectional study conducted in the Gynaecology OPD at a tertiary care centre in Chennai. 3o postmenopausal women in the age group of 45 and above were chosen for the study. Bone mineral density was measured by ultrasound bone densitometer and expressed as T score. Serum 25 hydroxy vitamin D levels were estimated by Chemiluminescence method. The data was analysed using SPSS software version 16. Results: T score of all the subjects ranged between -2.5 to -4.25. The mean serum 25-hydroxy Vitamin D level was 16.6 ± 4.8 ng/ml. Pearson correlation analysis was done. A significant correlation was seen between Age and Bone Mineral Density (p<0.000), 25- hydroxy Vitamin D and Bone Mineral Density (p<0.000), age and 25- hydroxy Vitamin D (p<0.000). Interpretation: In this study the T score of all the subjects ranged from -2.5 to -4.25 which is suggestive of osteoporosis. In this study 37% of the subjects had 25-hydroxy Vitamin D levels less than 20ng/ml suggestive of Vitamin D Deficiency. Conclusion: Vitamin D could be an important factor implicated in the development of osteoporosis in these post-menopausal women.
Authors and Affiliations
Madhubala V, Anusha R
Keywords
Related Articles
- EP ID EP297426
- DOI 10.18231/2394-6377.2017.0077
- Views 64
- Downloads 0
Prevalence of High Lipid Profile in Diabetes Meellitus Patients: A Study in a Tertiary Care Centre
Introduction: Diabetes mellitus is a group of metabolic diseases characterized by increased blood glucose levels resulting from defects in insulin secretion, insulin action, or both. It is also associated with interrelat...
Status of high sensitive C- reactive protein (hs-CRP) in NAFLD obese type-2 diabetic subjects
Introduction Non alcoholic fatty liver disease NAFLD is a disease occurring in patients without any significant alcohol consumption It includes a broad spectrum and advanced forms of liver diseases from simple steatosis...
Role of Lipids in type 2 diabetes mellitus for causation of coronary artery disease
Diabetes is characterized by chronic hyperglycemia and disturbances of carbohydrate, protein and lipid metabolism. The present study was undertaken to research the association between serum lipid profile, its abnormaliti...
Study of evaluation of lipid profile and phosphorus levels in acute myocardial infarction patients
Introduction: Myocardial infarction is the leading cause of mortality and morbidity in present days. Sometimes, especially in early period, features of MI may not be fully developed. Like chest pain is the most common pr...
Study of serum high sensitive C-Reactive protein and ferritin in preterm labor
Introduction: Preterm delivery is estimated to be one of the leading causes of perinatal morbidity and mortality, for which there are no known effective preventive measures. C - reactive protein (CRP) is one of the sensi...