Serum H Pylori Antibodies and Thyroid Disorder in Chronic Urticaria
Journal Title: IOSR Journal of Biotechnology and Biochemistry (IOSR-JBB - Year 2018, Vol 4, Issue 2
Abstract
Introduction:Chronic urticaria(CU) is the most common pruritic condition with multiple casual factor characterized by erythamatous, edematous and pruritic lesion of dermis and hypodermis 50% of patients with chronic urticaria have autoimmune basis. Thyroid disorders and H pylori have been a major contribution to chronic urticaria. AIMS and objectives: To estimate RBS, H pylori IgG, IgM, TSH in patients with chronic urticaria and comparing with control group. To evaluate the importance of these biochemical parameters in chronic urticaria patients. Methodology:30 patients with symptoms of chronic urticaria and 28 controls were considered for the study. Random Blood samples was collected and evaluated for H pylori IgG, IgM, RBS and TSH. H pylori antibodies was analysed by Elisa method. TSH was estimated by immunoassay method and RBS by hexokinase- G6PD method. Results:RBS in cases and controls was 119.07 ± 62.9 and 90.67 ± 11.17, respectively with significant p value of 0.022. TSH in cases and controls was 4.11 ± 2.26 and 2.47 ± 1.42, respectively with significant p value of 0.02. H pylori IgG in cases and controls was 0.83 ± 0.58 and 0.46 ± 0.43, respectively with significant value of 0.034. H pylori IgM in cases and controls was 0.79 ± 0.55 and 0.52 ± 0.35, respectively, with significant value of 0.028. Conclusion:RBS, TSH, H pylori IgG and IgM was significantly high in cases than controls, suggesting a strong role of diabetes, and autoimmune role in urticaria.
Authors and Affiliations
Shantha Kumari . N, Karthik G, Nataraj B
Keywords
Related Articles
- EP ID EP415053
- DOI 10.9790/264X-0402010911.
- Views 131
- Downloads 0
Efficacy of Annona squamosa (L.) extracts in controlling Diabetes Mellitus in Mice diabetic models
Diabetes mellitus (DM) is a metabolic disorder of multiple etiologies characterized by absolute or relative deficiency of insulin secretion with or without varying degree of insulin resistance. Sedentary life style and o...
Generating Cyan Fluorescent Protein (CFP) From Green Fluorescent Protein (GFPUV) By Y66w Mutation
This work seeks to generate CFP from GFPuv by Y66W mutation. Specific objectives include site directed mutagenesis on GFPuv and sequence alignment of generated CFP with wild type GFPuv and fluorimetry studies of CFP in r...
Screening Selected Cassava Cultivars for Resistance against Cassava Viruses and Cassava Green Mites under Advanced Yield Trials in Kenya
Cassava (Manihot esculenta Crantz) is one of the most cultivated tuberous crops as a sustainable source of food security and family income among the poor in the developing world. Despite this economic significance, cassa...
External Quality Assurance Scheme (EQAS): Criteria for Evaluating Performance of a Laboratory
Introduction: External Quality Assessment Scheme (EQAS) involves evaluation of a number of laboratories by an outside agency on the performance of a number of laboratories based on their analytical performance of tests o...
Iron Deficiency Anemia In Pregnancy: Pre And Post Iron Sucrose Therapy In A Tertiary Referral Centre
Introduction: Iron deficiency is commonly prevalent in women of reproductive age group.Early detection of iron stores before the development of anemia is beneficial. The maternal iron level is important for the growth of...