Serum Hepcidin Concentration is Elevated during Malaria Infection among Children in Sokoto Nigeria

Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2018, Vol 13, Issue 1

Abstract

:Malaria and iron deficiency are major public health problems for children living in sub-Saharan Africa. This study was aimed at evaluating serum hepcidin concentration dynamics during malaria infection among children in Sokoto, North-Western Nigeria. 402 children were enrolled in this study, comprising 200 males (49.8%) and 202 females (51.2%) aged between 1 – 17 years. The prevalence of malaria infection in this study was 31.3%, with subjects within the ages of 11 – 15 years having the highest prevalence (29.6%). Significant differences were observed for serum hepcidin concentrationand other iron indices between malaria infected children and non-malaria infected children, (control) (p < .05). Serum hepcidin concentration is increased during malaria infection among children in our study population (p < .05).We concluded that determination of serum hepcidin concentration in synergy with other iron parameters may be a useful marker in the prognosis and management of malaria infection in our setting.

Authors and Affiliations

Teddy Charles Adias, Jafaru Musa Aliyu, Osaro Nelson Erhabor, Diweni Pere Dick

Keywords

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  • EP ID EP393466
  • DOI 10.9790/3008-1301043741
  • Views 85
  • Downloads 0

How To Cite

Teddy Charles Adias, Jafaru Musa Aliyu, Osaro Nelson Erhabor, Diweni Pere Dick (2018). Serum Hepcidin Concentration is Elevated during Malaria Infection among Children in Sokoto Nigeria. IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS), 13(1), 37-41. https://europub.co.uk/articles/-A-393466