Serum Hepcidin Concentration is Elevated during Malaria Infection among Children in Sokoto Nigeria
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2018, Vol 13, Issue 1
Abstract
:Malaria and iron deficiency are major public health problems for children living in sub-Saharan Africa. This study was aimed at evaluating serum hepcidin concentration dynamics during malaria infection among children in Sokoto, North-Western Nigeria. 402 children were enrolled in this study, comprising 200 males (49.8%) and 202 females (51.2%) aged between 1 – 17 years. The prevalence of malaria infection in this study was 31.3%, with subjects within the ages of 11 – 15 years having the highest prevalence (29.6%). Significant differences were observed for serum hepcidin concentrationand other iron indices between malaria infected children and non-malaria infected children, (control) (p < .05). Serum hepcidin concentration is increased during malaria infection among children in our study population (p < .05).We concluded that determination of serum hepcidin concentration in synergy with other iron parameters may be a useful marker in the prognosis and management of malaria infection in our setting.
Authors and Affiliations
Teddy Charles Adias, Jafaru Musa Aliyu, Osaro Nelson Erhabor, Diweni Pere Dick
Keywords
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- EP ID EP393466
- DOI 10.9790/3008-1301043741
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