Serum paraoxonase-1 activities and malondialdehyde levels in patients with epilepsy
Journal Title: Dicle Tıp Dergisi - Year 2012, Vol 39, Issue 4
Abstract
Objectives: We aimed to evaluate antioxidant paraoxonase- 1 (PON-1) activity together with malondialdehyde (MDA) (an oxidative stress parameter) levels in patients with epilepsy. Materials and methods: Forty-five epilepsy patients were included in the study and compared with healthy controls (n = 45). The levels of serum MDA and PON-1 activities were measured by the Ohkawa method and the Eckerson method, respectively. Results: Serum MDA level was significantly higher (P = 0.015), whereas PON-1 activity was sigificantly lower (P = 0.011) in the patient group than the controls. Conclusions: Increased reactive oxygen species levels in epilepsy may result in a oxidative stress, which in turn could result in decreased antioxidant PON-1 activity and increased MDA levels. Key words: Epilepsy, oxidative stress, malondialdehyde, paraoxonase-1
Authors and Affiliations
Mehmet Çevik, Sefer Varol, Yavuz Yücel, Eşref Akıl, Tahsin Çelepkolu, Adalet Arıkanoğlu, Hatice Yüksel
Keywords
Related Articles
- EP ID EP135456
- DOI -
- Views 124
- Downloads 0
Üst gastrointestinal sistem yabancı cisimleri
Amaç: Üst gastrointestinal sistem (GİS) yabancı cisimlerine özellikle çocuklarda sık karşılaşılır. Erişkin yaş grubunda daha seyrek görülmekte ancak daha yüksek oranda morbitide ve mortaliteye yol açabilmektedirler. Y...
The evaluation of the clinical and laboratory characteristics of children with pulmonary tuberculosis
Objective: Pulmonary tuberculosis is an important health problem in pediatric patients. The aim of this study is to evaluate the epidemiological and clinical signs and treatment results of the children with pulmonary tu...
Brusella jel aglütinasyon testinin diğer Brusella testleri ile karşılaştırılması
Amaç: Bu çalışmada, bruselloz ön tanısı konmuş hastalarda tanı testlerinin duyarlılığını karşılaştırılması ve hassasiyetlerinin ölçülmesi amaçlanmıştır. Yöntem: Serolojik yöntemlerden, Standart Tüp Aglütinasyon Testi,...
Magnetic resonanse imaging findings of redundant nerve roots syndrome
Objectives: The purpose of our study was to determine the findings of redundant nerve roots syndrome (RNRS) in lumbar stenosis by magnetic resonance (MR) imaging. Materials and methods: A total of 8906 lumber MR imagi...
Üçüncü basamak bir hastanede, geriatrik olgularda izole edilen candida türlerinin tiplendirilmesi ve kanda üreyen mayalarda antifungal duyarlılık
Amaç: Çalışmamızda, hastanemize başvuran geriatrik olguların kan ve idrar örneklerinden izole edilen Candida türlerinin tiplendirilerek dağılımının belirlenmesi ve kandan soyutlanan Candida türlerinin antifungal duyarlı...