The effect of serum 25(OH) vitamin D on hemogram parameters
Journal Title: Dicle Tıp Dergisi - Year 2014, Vol 41, Issue 2
Abstract
Objective: Vitamin D that has pleiotropic hormone characteristics is a fat soluble vitamin. In general, vitamin D is known to be associated with rickets, but the studies show that vitamin D also acts on tissues and cells other than bone itself. In this study, we aimed to investigate if vitamin D has any effects on hemogram parameters or not. Methods: This retrospective study was done with the data obtained from 243 female and 59, totally 302 patients. Vitamin D level and hemogram parameters [(red blood cell (RBC), hemoglobin (Hb), white blood cell (WBC), platelet (PLT), mean platelet volume (MPV), and red cell distribution width (RDW)] of patients were obtained. Patients were divided into 4 groups according to their levels of vitamin D: Group 1: < 10 ng/mL; Group 2: 10-19 ng/mL; Group 3: 20-29 ng/mL, and Group 4: 30-60 ng/mL. Results: There were no significant differences in RBC, Hb, WBC, PLT, MPV, and RDW between the groups (p>0.05). Also, there was no correlation between the hemogram parameters and vitamin D. Conclusion: According to the literature, there are a lot of studies that show the relationship between vitamin D and WBC, RBC, and PLT. However, contrary to the previous studies, we were unable to find any significant relationship between vitamin D and hemogram parameters. These results serve the idea that the effects of vitamin D on the hematopoietic system should be further investigated experimentally and clinically. Key words: Vitamin D, WBC, RBC, PLT, Hemoglobin
Authors and Affiliations
Gülfer Öztürk, Erdem Bulut, Sümeyya Akyol, Mine Taşlıpınar, Zeynep Giniş, Fatma Uçar, Gönül Erden
Keywords
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- EP ID EP105169
- DOI 10.5798/diclemedj.0921.2014.02.0426
- Views 126
- Downloads 0
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