Serum sialic acid and its lipid and protein bounds as possible biomarkers of acute myocardial infarction in Erbil city
Journal Title: ZANCO JOURNAL OF MEDICAL SCIENCES - Year 2011, Vol 15, Issue 1
Abstract
Backgrounds and objectives: Myocardial infarction (MI) usually occurs when coronary blood flow decreases abruptly after a thrombotic occlusion of a coronary artery previously affected by atherosclerosis. Sialic acid (SA) is attached to non reducing residues of the carbohydrate chains of glycoproteins and glycolipids. An elevation in seru TSA, LBSA and PBSA concentrations has been observed in a number of pathological conditions .The aim of the study was to determine the serum TSA and its LBSA and PBSA in patients with acute myocardial infarction (AMI). Methods: Serum TSA, LBSA and PBSA concentrations were evaluated by UV/VIS spectrophotometry in (100) apparently healthy individuals and (100) newly diagnosed AMI patients. Results: The mean levels of serum TSA, LBSA and PBSA in AMI patients were significantly higher (P< 0.5) than those of apparently healthy individuals. Conclusion: The results indicate that the serum values of TSA, LBSA and PBSA appeared to be of a value in diagnosis of AMI. Key wards: AMI, TSA, LBSA, PBSA.
Authors and Affiliations
Rasul Sulayman Aziz , Tayfoor Jalil Mahmoud , Hamid G. Hassan
Keywords
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