Serum soluble interleukin-6 receptor concentration measurament in patients with systemic sclerosis before and after immunosupressive therapy
Journal Title: Postępy Dermatologii i Alergologii - Year 2006, Vol 23, Issue 2
Abstract
The aim of this study was to asses the usefulness of soluble interleukin-6 receptor (sIL-6R) concentration in assesment of disease severity and treatment effects in systemic sclerosis (SSc) using immunosupressive agents. Seventeen patients with rapidly progressive SSc were treated with oral cyclophosphamide and prednisone for 6–60 months. The concentration of sIL-6R was measured by ELISA in the preatretment and posttreatment serum samples from the SSc patients and from 15 healthy women as controls. Pretreatment and postretment mean level of sIL-6R was significantly increased compared with normal controls, p
Authors and Affiliations
Anna Lis-Święty, Ligia Brzezińska-Wcisło, Iwona Rogala-Poborska, Ewa Syguła
Keywords
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