Severe Hepatic-Neurological Complications of Dengue Fever in Children from a Tertiary Care Center in North India
Journal Title: Journal Of Pediatric Critical Care - Year 2016, Vol 3, Issue 3
Abstract
Objective To present clinical experience and outcome of severe hepatic-neurological complications of dengue fever. Methods-From August to November 2015, all confirmed dengue cases admitted to Pediatric intensive care unit(PICU) were studied and data was retrospectively collected and analyzed. Results-Out of 196 confirmed dengue cases 11 had severe hepatic-neurological complications Neurological complications were seen in 7 patients of which 2 had meningoencephalitis, 2 had meningitis and 3 had seizures. All recovered completely except one who had sequelae. Acute liver failure occurred in 4 and 3 recovered completely except one who expired. Conclusions-Use of N-acetylcysteine in ALF is found to be beneficial. In our experience outcome of these complications is good, however larger trials are needed to investigate further.
Authors and Affiliations
Pradeep kumar Sharma, Maneesh Kumar, Ashish Sahani, Rohit Goyal
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