Significance of Effect of Metformin on Cancer Stem Cells – “Need of an Hour” in oral cancer
Journal Title: Journal of Research in Medical and Dental Science - Year 2017, Vol 5, Issue 5
Abstract
Oral cancer is a life-threatening disease. Advanced therapeutic approaches are still insufficient to improve the prognosis. Effect of Metformin on cancer stem cells (CSCs) provides promising future. Research on diverse molecular mechanisms involved in different kinds of cancers showed a definite correlation. The role in oral squamous cell carcinoma(OSCC) is not yet defines. So, it will be fruitful in future if the research on metformin and CSCs would be done in oral cancer. It would be helpful in improving the results of current antitumor treatment in oral cancer
Authors and Affiliations
Anjali P Ganjre, Supriya Kheur, Vivek Pawar, Madhura V Pawar
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