Silent Brain Infarcts in Patients with Non-Specific Neurological Symptoms: 1-Year Cross-Sectional Study
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 1
Abstract
Background: Silent brain infarctions are considered as a preclinical warning of symptomatic strokes and multiple deep infarct-relatedbrain damage.Limitation of studies on risk factors and non-specific neurological symptoms in the Indian population led to the formulation of the present study. Aim: To evaluate the presence of silent brain infarctions in patients with non-specific neurological symptoms and association with cardiovascular risk factors. Methods: This cross-sectional study was conducted from January to December 2010, including patients with non-specific neurological symptoms (n = 51). General and neurological assessment with Mini-Mental Scale Examination were conducted after recording the demographic data, body mass index, and cardiovascular risk factors. T2-weighted magnetic resonance imaging was performed with repetition time of 4500 ms and echo time of 116 ms. Scans were processed with double-blind method. Particle-enhanced turbidimetric immunoassay technique was performed for assessing high-sensitivity C-reactive protein. Results: The major non-specific neurological symptoms were headache (54.90%), dizziness (23.53%),and vertigo (25.49%). Out of 51 patients, 29.41% were diagnosed with silent brain infarction. Cortical (26.6%) and sub cortical (73.4%) nature of infarction was recorded. The association of risk factors with silent brain infarction was not significant. Conclusion: Patients with non-specific neurological symptoms should be examined for silent brain infarction. Follow-up study can be conducted with large sample size to evaluate the association of the risk factors with infarction and stroke.
Authors and Affiliations
Dr Prakash Babaliche
Keywords
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